Ethnobotanical and antimicrobial investigation on some species of Terminalia and Combretum (Combretaceae) growing in Tanzania

Fyhrquist, Pia; Mwasumbi, Leonard; Hæggström, Carl-Adam; Vuorela, Heikki; Hiltunen, R.; Vuorela, Pia

doi:10.1016/s0378-8741(01)00375-0

Cited by 166 publications

(131 citation statements)

References 22 publications

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“…The MIC was determined for the antibacterial most efficient extracts, using the cylinder agar diffusion method as described by (Fyhrquist et al, 2002).…”

Section: Determination Of Minimum Inhibitory Concentration (Mic)mentioning

confidence: 99%

Antibacterial Activity of Volatile Oil of Ixora Cocciniea Against Burn Isolates.

Pria¹,

Shanmugapriya

2015

JNS

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Volatile oils are one of the groups of secondary metabolites produced by some plants. Their probable users against burn microbes have received little attention. Burn swabs obtained from ten burned patients at Government hospital, led to the isolation of bacteria using standard methods, the microorganisms were isolated. Then chloroform, methanol and aqueous extract of volatile of Ixora Cocciniea against S.aureus, E.coli, Pseudomonas aeruginosa, P.vulgaris and K.pnemoniae exhibited antibacterial were found efficacious respectively.

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“…The MIC was determined for the antibacterial most efficient extracts, using the cylinder agar diffusion method as described by (Fyhrquist et al, 2002).…”

Section: Determination Of Minimum Inhibitory Concentration (Mic)mentioning

confidence: 99%

Antibacterial Activity of Volatile Oil of Ixora Cocciniea Against Burn Isolates.

Pria¹,

Shanmugapriya

2015

JNS

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“…The plant has wide spread traditional uses in eastern and southern African countries (Arnold and Gulumian, 1984;Kokwaro, 1976;Msonthi and Magombo, 1983). Among some of its proven biological activities, include inhibition of topoisomerase II (Wall et al, 1996), antibacterial, and antifungal activity (Eloff, 1999;Fyhrquist et al, 2002;2004). However, there is scanty information on compounds that are responsible for the exhibited biological activities of the plant.…”

Section: Introductionmentioning

confidence: 99%

Isolation Of A Stilbene Glycoside And Other Constituents Of <i>Terminalia sericeae</i>

Joseph

Moshi²,

Innocent³

et al. 2008

Afr. J. Trad. Compl. Alt. Med.

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The ethanol extract of the root bark of Terminalia sericea yielded an unreported stilbene glycoside, 3'5'-dihydroxy-4-(2-hydroxy-ethoxy) resveratrol-3-O-β-rutinoside (1) together with known compounds resveratrol-3-β-rutinoside glycoside (2), 3',4,5'-Trihydroxystilbene (resveratrol) (3), triterpenoic acid arjungenin and a mixture of β-sitosterol and stigmasterol. Structure determination of the isolated compounds was achieved on the basis of spectroscopic measurements.

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“…Despite wide use of C. molle as medicinal plant for treatment of various ailment including helminthic, protozoal, bacterial and other infectious diseases in different parts of Africa (McGaw et al, 2001;Fyrquist et al, 2002;Bussmann et al, 2006;Grønhaug et al, 2008), studies conducted on its in vivo toxicity test is scanty. According to the traditional practice of the local community, the seed of the plant is used after it is extracted by water as a solvent.…”

Section: Discussionmentioning

confidence: 99%

“…Author(s) agree that this article remain permanently open access under the terms of the Creative Commons Attribution License 4.0 International License dysentery, general body swellings, and abortion as well as for swelling of the abdomen, sterility and constipation (Fyhrquist et al, 2012). This plant bark and root in vitro tested in different African countries for treatment of bacteria (Sahlu, 2013;Regassa and Araya, 2012).…”

Section: Introductionmentioning

confidence: 99%

Effect of Combretum molle (Combretaceae) seed extract on hematological and biochemical parameters

Anato¹,

Bezabih²,

Ketema³

2018

J. Med. Plants Res.

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Combretum molle (Combretaceae) is widely used traditional medicinal plant for treatment of different illnesses in most parts of Africa. However, its in vivo toxic effect is not evaluated yet. Thus, the aim of this study was to evaluate cytotoxic effect of C. molle seed extract on biochemical and hematological parameters using mice. Accordingly, effect of seed extract of the plant on hematological and biochemical parameters and on tissues of different organs were determined. Blood sample collected on the next day of the last dose administration was used for further analysis. Organs were collected in formalin for histological study. Result of the study showed that seed extract of C. molle did not cause significant effects on most red blood cells (RBCs) indices. Also, except eosinophil count, all white blood cells (WBCs) indices showed significant reduction (P<0.05) under use of almost all doses of the seed extract. Level of liver enzymes such as glutamic oxaloacetate transaminase (sGOT) and glutamic pyruvic transaminase (sGPT) showed significant increment (P<0.05) in mice treated with different doses of the plant seed extract, while concentration of albumin was significantly reduced (P<0.05). Similarly, significant increament (P<0.05) in levels of kidney function indicators urea and creatinine was observed. At relatively lower dose (125 mg/kg), the crude extract of C. molle seed showed lower effects on haematological, biochemical and immunological parameters. As dose increased, its cytotoxic effect increased.

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Ethnobotanical and antimicrobial investigation on some species of Terminalia and Combretum (Combretaceae) growing in Tanzania

Cited by 166 publications

References 22 publications

Antibacterial Activity of Volatile Oil of Ixora Cocciniea Against Burn Isolates.

Antibacterial Activity of Volatile Oil of Ixora Cocciniea Against Burn Isolates.

Isolation Of A Stilbene Glycoside And Other Constituents Of <i>Terminalia sericeae</i>

Effect of Combretum molle (Combretaceae) seed extract on hematological and biochemical parameters

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