This study investigates Black and White consumers’ preferences for Black versus White people in United States advertising contexts over 66 y, from 1956 until 2022, a time in which the United States has experienced significant ethno-racial diversification. Examining Black and White consumers’ reactions to visual advertising over more than half a century offers a unique and dynamic view of interracial preferences. Mass advertising reaches an audience of billions and can shape people’s attitudes and behavior, emphasizing the relevance of clarifying the influence of race in advertising, how it has evolved over time, and how it may contribute to mitigating discrimination based on racial perceptions. A meta-analysis of extant experiments into the relationship between the depicted endorser’s race (i.e., the model in a visual ad) and the reaction of Black and White viewers pertains to 332 effect sizes from 62 studies reported in 52 scientific papers, comprising 10,186 Black and White participants. Our results are anchored in a conceptual framework, including a comprehensive set of perceiver (viewer), target (endorser), social/societal context, and publication characteristics. Without accounting for temporal dynamics, the results indicate ingroup favoritism, such that White viewers prefer White models and Black viewers prefer Black models. But by controlling for the publication year, it is possible to observe a time-dependent trend: Historically, White consumers preferred endorsers of the same race, but this preference has significantly shifted toward Black endorsers in recent years. In contrast, the level of Black consumers’ reactions to endorsers of the same race remains largely unchanged over time.