Ethnic differences in lens parameters measured by ocular biometry in a cataract surgery population

Wang, Dajiang; Amoozgar, Behzad; Porco, Travis C.; Wang, Zhen; Lin, Shan

doi:10.1371/journal.pone.0179836

Cited by 32 publications

(45 citation statements)

References 45 publications

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“…In the study among black south Africans, the mean LT was 3.69 (± 0.25) mm while a study comparing ethnic differences in lens parameters found the average measurements in whites 4.52 (0.46) mm, African American 4.48 (±0.54) mm, Asians 4.60 (±0.46) mm, and Hispanics 4.53 (±0.44) mm. 21 In our study, age, height, and BMI have a significant association in the univariable analysis but only age ( p -value <0.001) persisted after adjustment. This is in keeping with other studies.…”

Section: Discussioncontrasting

confidence: 41%

<p>Ocular Biometry and Their Correlations with Ocular and Anthropometric Measurements Among Ethiopian Adults</p>

Gessesse

Debela

Anbesse

2020

OPTH

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Purpose: To determine the average values of ocular biometry dimensions and investigate their inter-correlations and their association with anthropometric measurements among Ethiopian adults with healthy eyes. Methods: A cross-sectional study was undertaken from June 2018 to July 2019. A total of 400 eyes of 200 subjects were included in the study. Univariable and multivariable linear regression were used to determine the association of demographic variables (age and sex) and anthropometric parameters (height, weight and BMI) with ocular biometric indices. Results: The mean age was 40.31±11.39 with a range from 18 to 69 years. The mean (SD) of horizontal corneal diameter, average corneal refractive power, anterior chamber depth (ACD), lens thickness (LT) and axial length (AL) were 11.45 (0.89) mm, 43.94 (9.78) diopter, 2.91 (0.43) mm, 4.29 (0.55) mm and 22.96 (0.82) mm, respectively. Age had a negative correlation with ACD (r= −0.196, p= <0.001) and positive correlation with lens thickness (r= 0.324, p<0.001). Height had a positive correlation with ACD (r=0.114, p=0.023) and LT (r= 0.206, p=<0.001) while negative correlation with LT (r=−0.129, p=0.01). In the multivariate linear regression, age (−0.009 (−0.013, −0.05), p-value <0.001) and sex (0.104 (0.01, 0.198), p-value=0.03) had a significant association with ACD and only gender (0.478 (0.302, 0.654), p-value <0.001) had a statistically significant association with lens thickness. Conclusion: This study determined the normative values for ocular biometric parameters among Ethiopian adults for the first time. Age, gender and height were associated with biometric indices. AL was significantly positively correlated with ACD and negatively correlated with LT. There was a negative correlation between LT and both AL and ACD.

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Section: Discussioncontrasting

confidence: 41%

<p>Ocular Biometry and Their Correlations with Ocular and Anthropometric Measurements Among Ethiopian Adults</p>

Gessesse

Debela

Anbesse

2020

OPTH

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“…The thickness of the crystalline lens varies depending on age and race [10, 11], so measured axial length values in the same eye may differ between measurements made using the individual refractive indices and those made using the equivalent refractive index; the error of the intraocular lens (IOL) power calculation may also show discrepancy between the two biometers.…”

Section: Introductionmentioning

confidence: 99%

Clinical Evaluation of a New Swept-Source Optical Coherence Biometer That Uses Individual Refractive Indices to Measure Axial Length in Cataract Patients

et al. 2019

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Backgrounds: Although the OCT biometer using individual refractive index is available, comparisons of measurement value and intraocular lens (IOL) power calculation error with other SS-OCT biometers are not known. Objectives: To compare the new SS-OCT biometer ARGOS (OCTB1), which uses individual refractive indices to measure axial length, with the IOLMaster 700 (OCTB2) and OA-2000 (OLCR), which use equivalent refractive index. Method: Six hundred and twenty-two eyes of 622 patients who had been diagnosed with cataract were enrolled in the study. Among the 158 eyes that had undergone cataract surgery, the postoperative refractive error was evaluated using the Haigis formula. Results: The axial length measured by the OCTB1 showed a proportional bias in comparison with the other two biometers and a fixed bias in eyes with an axial length ≥26 mm. No significant difference was found in the median absolute refractive prediction error (p = 0.3278). However, in eyes with an axial length ≥26 mm, the OCTB1 showed myopic error compared with the other two biometers (p < 0.0001). Conclusions: In eyes with long axial length, when the conventional IOL calculation was optimized with the equivalent refractive index-based instrument, we need to consider that IOL calculation using OCTB1 tends to cause slightly myopic refractive prediction error.

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“…Considering the wide prevalence of cataract and cataract–related blindness in developing countries and, specifically, in Iran ( 19 ), and with a rapidly aging population, this problem is predicted to multiply in future. The ethnic differences in ocular parameters have suggested that the surgical outcome of cataract surgery may be different in different ethnicities/races ( 20 , 21 ), while to the best of our knowledge, there are few studies in our country investigating the post-operative complications of cataract surgery ( 22 ). Considering the increased cataract surgical rate in our country from about 2.5 times from 526 to 1,331 per million over five years (2000–2005) ( 23 ), it is necessary to determine the surgical outcome of cataract surgery in Iranian patients.…”

Section: Introductionmentioning

confidence: 99%

Changes in corneal thickness and corneal endothelial cell density after phacoemulsification cataract surgery: a double-blind randomized trial

Bamdad¹,

Bolkheir²,

Sedaghat³

et al. 2018

Electron Physician

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BackgroundAge-related cataract is a leading cause of visual impairment, considered a global health burden, it is responsible for over 47% of blindness worldwide. Surgical intervention is usually the treatment of choice and phacoemulsification cataract surgery with implantation of an intraocular lens is the most common procedure, which may have several complications.ObjectivesTo determine the effects of phacoemulsification surgery on corneal endothelial cell density and corneal thickness in patients undergoing cataract surgery.MethodsThe present study was conducted on patients diagnosed with immature senile cataract requiring surgical intervention from November 2013 to 2014 in Khatam al Anbia Hospital (a tertiary ophthalmology center). Physical examination included best-corrected visual acuity using the Snellen chart, refraction, slit-lamp bio-microscopy for anterior chamber evaluation, keratometry, Goldman tonometry, gonioscopy, and dilated indirect ophthalmoscopy, pachymetry, specular microscopy and biometry. Surgery was performed by similar method and technique in all patients. The change in the corneal endothelial cell count or density and central corneal thickness (CCT) number were compared preoperatively and one day, one week, one month, and three months post–operatively.ResultsA total of 92 eyes of 85 patients (43 females and 42 males with mean age of 62.1±12.2 years) were studied. Patients’ visual acuity improved (log MAR: 1±0.5 preoperatively to 0.45±0.34 post-operatively) (p=0.001). There was 11.4% endothelial cell loss (ECL) and significant decrease in ECC (from 2,791.15±99.86 to 2,472.87±472.14) (p=0.04). The central corneal thickness increased significantly (from 530.47±2.60 to 540.91±36.07). Diabetic patients (12.9%) had a statistically significant higher ECL rate after phacoemulsification (14.6% versus 8.7% respectively, p=0.002).ConclusionPhacoemulsification resulted in significant corneal endothelial damage, which is particularly important in patients with a borderline reservoir of endothelial cell, such as diabetic patients, which highlights the necessity of refining the current surgical methods and instruments to minimize the endothelial damage.Trial registrationThe trial was registered in the Thai clinical trial registry (http://www.clinicaltrials.in.th) with the ID: TCTR20171122001.FundingThe study was supported by a research grant of Mashhad University of Medical Sciences.

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Ethnic differences in lens parameters measured by ocular biometry in a cataract surgery population

Cited by 32 publications

References 45 publications

<p>Ocular Biometry and Their Correlations with Ocular and Anthropometric Measurements Among Ethiopian Adults</p>

<p>Ocular Biometry and Their Correlations with Ocular and Anthropometric Measurements Among Ethiopian Adults</p>

Clinical Evaluation of a New Swept-Source Optical Coherence Biometer That Uses Individual Refractive Indices to Measure Axial Length in Cataract Patients

Changes in corneal thickness and corneal endothelial cell density after phacoemulsification cataract surgery: a double-blind randomized trial

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