Ethics and blood donation: A marriage of convenience

Tissot, Jean‐Daniel; Garraud, Olivier

doi:10.1016/j.lpm.2016.06.016

Cited by 14 publications

(9 citation statements)

References 25 publications

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“…Furthermore, the frequency of donations also has a strong impact on donor safety and the depletion of iron stores. Finally, the ethics of donation or collection is now regarded as a strong pillar of safety ( 19 ).…”

Section: The “A B C” Of the Blood Collection And Transfusion Procesmentioning

confidence: 99%

How Can Eastern/Southern Mediterranean Countries Resolve Quality and Safety Issues in Transfusion Medicine?

2018

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Unlike their Western counterparts, some of the Eastern/Southern Mediterranean countries lack centralized coordinated blood transfusion services leading to an unequal blood safety level. This was recently highlighted by a recent World Health Organization (WHO) regional committee report in which WHO urges these countries to establish and implement a national blood system with well-coordinated blood transfusion activities and to make attempts to reach 100% voluntary non-remunerated blood donation. The objective is thus to meet the same levels or standards as Western countries in term of self-sufficiency and blood safety. This raises the question whether these countries can either comply with Western countries’ guidelines and experiences or develop their own safety scheme based on proper sociopolitical and economic features. Another option is to identify efficient and cost-effective strategies setup successfully in neighbor countries sharing cultural and economic features. To address this issue—and make an attempt to achieve this goal—we designed a number of surveys specifically addressed to Mediterranean countries, which were sent out to the national authorities; so far, five surveys aim at covering all aspects in blood collection, processing, testing, inventory and distribution, as well as patient immune-hematological testing and follow-up (including surveillance and vigilances). It is anticipated that such practice can help identifying and then sharing the more successful and cost-effective experiences, and be really focused on Mediterranean areas while not necessarily copying and pasting experiences designed for Western/Northern areas with significantly distinct situations.

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Section: The “A B C” Of the Blood Collection And Transfusion Procesmentioning

confidence: 99%

How Can Eastern/Southern Mediterranean Countries Resolve Quality and Safety Issues in Transfusion Medicine?

2018

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“…It is also assumed that plasma obtained from healthy donors imparts immunomodulatory effects through the infusion of antibodies and anti-inflammatory cytokines, which impedes the action of autoantibodies and inflammatory cytokines [64]. A standard pre-donation assessment of the convalescent donors is done as it is essential to adhere to the current plasma donation regulations [65]. Presently, convalescent donors between the age of 18 and 65 are regarded as subjects.…”

Section: Convalescent Plasma Therapy: Composition Of Plasma and Its Ementioning

confidence: 99%

“…They should be COVID-19 negative after 14 days and should not display any infective symptoms. These tests must be conducted again after 48 h and at the time of donation [54,65]. Plasma donors belong to areas with prevailing diseases (i.e.…”

Section: Convalescent Plasma Therapy: Composition Of Plasma and Its Ementioning

confidence: 99%

Convalescent plasma therapy: a promising coronavirus disease 2019 treatment strategy

Piyush

Rajarshi

Khan³

et al. 2020

Open Biol.

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The world is passing through a very difficult phase due to the coronavirus disease 2019 (COVID-19) pandemic, which has disrupted almost all spheres of life. Globally, according to the latest World Health Organization report (10 August 2020), COVID-19 has affected nearly 20 million lives, causing 728 013 deaths. Due to the lack of specific therapeutic drugs and vaccines, the outbreak of disease has spawned a corpus of contagious infection all over the world, day by day, without control. As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a very rapid infection rate, it is essential to develop a novel ameliorative and curative strategy as quickly as possible. Convalescent plasma (CP) therapy is a type of adaptive immunity that has already been found to be effective in confronting several infectious diseases from the last two decades. For example, CP therapy was used in the treatment of viral-induced diseases like SARS-CoV epidemics, Middle East respiratory syndrome coronavirus (MERS-CoV) pandemics, Ebola epidemics and H1N1 pandemic. In this review, we have mainly focused on the therapeutic role of CP therapy and its neutralizing effect to fight against the COVID-19 outbreak.

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“…Donated blood is humanity ( 7 , 8 ) and ideally, VNRD blood is “pure” humanity, yet replacement donation shares the values of assistance and cannot be considered non-altruistic, even if a certain degree of social pressure cannot be ruled out ( 3 ). Maybe the lowest common denominator is the root symbol of blood, its sacred characteristic, whatever sacred may mean to people, ranging from religious to atheistic sentiments ( 9 ).…”

Section: As the Essential Determinant In Transfusion Blood Representmentioning

confidence: 99%

Blood and Blood Components: From Similarities to Differences

Garraud

Tissot

2018

Front. Med.

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Blood transfusion is made possible because, in most countries and organizations, altruistic individuals voluntarily, anonymously, and generously donate (without compensation) either whole blood or separated components that are then processed and distributed by professionals, prior to being allocated to recipients in need. Being part of modern medicine, blood transfusion uses so-called standard blood components when relative to cellular fractions and fresh plasma. However, as will be discussed in this paper, strictly speaking, such so-called labile blood components are not completely standard. Furthermore, the prevalent system based on voluntary, non-remunerated blood donation is not yet universal and, despite claims by the World Health Organization that 100% of blood collection will be derived from altruistic donations by 2020 (postponed to 2025), many obstacles may hinder this ambition, especially when relative to the collection of the enormous amount of plasma destined for fractionation into plasma derivative or drugs. Finally, country organizations also vary due to the economy, sociology, politics, and epidemiology. This paper then, discusses the particulars (of which ethical considerations) of blood transfusion diversity and the consequences for donors, patients, and society.

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Ethics and blood donation: A marriage of convenience

Cited by 14 publications

References 25 publications

How Can Eastern/Southern Mediterranean Countries Resolve Quality and Safety Issues in Transfusion Medicine?

How Can Eastern/Southern Mediterranean Countries Resolve Quality and Safety Issues in Transfusion Medicine?

Convalescent plasma therapy: a promising coronavirus disease 2019 treatment strategy

Blood and Blood Components: From Similarities to Differences

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