This comprehensive rapid review meticulously evaluates the transformative influence of Vision 2030 on the healthcare sector in Saudi Arabia. Vision 2030, with its broad scope, targets an extensive overhaul of healthcare through infrastructure enhancement, digital health adoption, workforce empowerment, innovative public health initiatives, and advancements in quality of care and patient safety. By employing a rigorous analytical approach, this review synthesizes a broad spectrum of data highlighting Saudi Arabia’s significant progress toward establishing an accessible, efficient, and superior healthcare system. It delves into the kingdom’s alignment with global healthcare trends and its distinctive contributions, notably in digital health and public health, illustrating a proactive stance on future healthcare challenges. The analysis rigorously explores Vision 2030’s ambitious objectives and the concrete outcomes achieved, providing deep insights into the evolving healthcare landscape in Saudi Arabia. Furthermore, it assesses the global ramifications of these reformative efforts, emphasizing the pivotal themes of innovation, equity, and excellence as the foundation for future healthcare advancements. This review not only sheds light on Vision 2030’s extensive impact on Saudi healthcare but also positions the kingdom as an exemplar of healthcare innovation and reform on the global stage, offering valuable lessons for healthcare policy and practice around the world.