PLoS ONE volume 9, issue 5, Pe98329 2014 DOI: 10.1371/journal.pone.0098329 View full text
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Hyeong-Geug Kim, Jin-Seok Lee, Min-Kyung Choi, Jong-Min Han, Chang-Gue Son

Abstract: Myelophil, an ethanolic extract of Astragali Radix and Salviae Radix, has been clinically used to treat chronic fatigue and stress related disorders in South Korea. In this study, we investigated the protective effects of Myelophil on a whisker removal-induced psycho-emotional stress model. SD rats were subjected to whisker removal after oral administration of Myelophil or ascorbic acid for consecutive 4 days. Whisker removal considerably increased total reactive oxygen species in serum levels as well as cereb…

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