1991
DOI: 10.1111/j.1748-1716.1991.tb09243.x
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Ethanol may be used with the microdialysis technique to monitor blood flow changes in skeletal muscle: dialysate glucose concentration is blood‐flow‐dependent

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Cited by 95 publications
(85 citation statements)
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“…In adipose tissue and skeletal muscle the ethanol ratio has been used to study local blood flow around the microdialysis probe (Hickner et al, 1991;Galitsky et al, 1993). A thorough methodological evaluation of this technique was made in vitro and in vivo in skeletal muscle, including a direct comparison with the radioactive xenon-washout technique (Hickner et al, 1992;.…”
Section: Resultsmentioning
confidence: 99%
“…In adipose tissue and skeletal muscle the ethanol ratio has been used to study local blood flow around the microdialysis probe (Hickner et al, 1991;Galitsky et al, 1993). A thorough methodological evaluation of this technique was made in vitro and in vivo in skeletal muscle, including a direct comparison with the radioactive xenon-washout technique (Hickner et al, 1992;.…”
Section: Resultsmentioning
confidence: 99%
“…36,38 Ethanol concentrations were measured both in the perfusate and the dialysate. The blood flow was estimated as ethanol clearance by dividing dialysate concentration by perfusate International Journal of Obesity Hormone sensitive lipase and weight loss M Kolehmainen et al concentration.…”
Section: Microdialysismentioning
confidence: 99%
“…This issue was first raised when ethanol clearance from microdialysis perfusate was developed and validated [15] as a method of attaining a qualitative measure of local tissue blood flow at the site of microdialysis catheter insertion. Studies demonstrated that, in animals, gross changes in tissue blood flow alter the recovery of glucose by microdialysis [16] (i. e. an increase in local blood flow increases dialysate recovery of glucose) and similar findings have since been reported in human adipose and muscle tissues but with a less predictable effect of altered blood flow on the recovery of ECF lactate [17].…”
Section: Methodologic Considerationsmentioning
confidence: 61%