Ethanol extracts from twelve Curcuma species rhizomes in China: Antimicrobial, antioxidative and anti-inflammatory activities

Shi, Yaohui; Liang, Xinmiao; Chi, Lejing; Chen, Yubin; Liang, Linjie; Luo, Yijie; Zhang, Weicheng; Cai, Qiuyang; Wu, Xianyi; Tan, Zekai; Zhang, Lanyue

doi:10.1016/j.sajb.2021.04.003

Cited by 7 publications

(2 citation statements)

References 16 publications

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“…Its content in curcuminoids (curcumin, bis-demethoxycurcumin and demethoxycurcumin) are lower than in C. longa [96], thus explaining a lower contribution from this phytochemical class when researching the bioactivities of this herbal medicine. Still it was shown to be more effective reducing the TPA (12-O-tetradecanoylphorbol-13-acetate)-induced ear edema in BALB/c mice than ibuprofen, an effect that is accompanied by a significant reduction in COX-2 levels in ear tissues [97]. Other constituents that have been related with topical anti-inflammatory activity are those present in the volatile fraction of the tubers/rhizomes of the plant [98].…”

Section: Curcuma Aromaticamentioning

confidence: 99%

Anti-Inflammatory and Antioxidant Chinese Herbal Medicines: Links between Traditional Characters and the Skin Lipoperoxidation “Western” Model

Prieto

Schinella

2022

Antioxidants

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The relationship between lipid peroxidation and inflammation has been accepted as a paradigm in the field of topical inflammation. The underlying biochemical mechanisms may be summarised as unspecific oxidative damage followed by specific oxidative processes as the physio pathological response in skin tissues. In this experimental review we hypothesise that the characteristics attributed by Traditional Chinese Medicine (TCM) to herbal drugs can be linked to their biomolecular activities within the framework of the above paradigm. To this end, we review and collect experimental data from several TCM herbal drugs to create 2D-3D pharmacological and biochemical spaces that are further reduced to a bidimensional combined space. When multivariate analysis is applied to the latter, it unveils a series of links between TCM herbal characters and the skin lipoperoxidation “Western” model. With the help of these patterns and a focused review on their chemical, pharmacological and antioxidant properties we show that cleansing herbs of bitter and cold nature acting through removal of toxins—including P. amurense, Coptis chinensis, S. baicalensis and F. suspensa—are highly correlated with strong inhibition of both lipid peroxidation and eicosanoids production. Sweet drugs—such as A. membranaceus, A. sinensis and P. cocos—act through a specific inhibition of the eicosanoids production. The therapeutic value of the remaining drugs—with low antioxidant or anti-inflammatory activity—seems to be based on their actions on the Qi with the exception of furanocoumarin containing herbs—A. dahurica and A. pubescens—which “expel wind”. A further observation from our results is that the drugs present in the highly active “Cleansing herbs” cluster are commonly used and may be interchangeable. Our work may pave the way to a translation between two medical systems with radically different philosophies and help the prioritisation of active ingredients with specific biomolecular activities of interest for the treatment of skin conditions.

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Section: Curcuma Aromaticamentioning

confidence: 99%

Anti-Inflammatory and Antioxidant Chinese Herbal Medicines: Links between Traditional Characters and the Skin Lipoperoxidation “Western” Model

Prieto

Schinella

2022

Antioxidants

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“…Primarily grown in southern provinces such as Sichuan, Fujian, Zhejiang, and Guangxi, this plant has historically been employed to ameliorate conditions such as blood blockage, dysmenorrhea, and trauma (Ni et al 2021). In addition, its volatile oils, curcumin analogs, and trace elements are recognized for their substantial medicinal attributes, encompassing anti-in ammatory (Hou et al 2015), antibacterial, antiviral, antitumor, and antipathogen effects (Shi et al 2021).…”

Section: Introductionmentioning

confidence: 99%

The Identification and Characterization of a New Species, Neopestalotiopsis Strain CP1, a Pathogen Causing Leaf Blight on Curcuma phaeocaulis in Guangxi, China

Li,

Long,

Guo

et al. 2023

Preprint

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Zedoary turmeric (Curcuma phaeocaulis), a cornerstone of traditional Chinese medicines in Guangxi Province, holds immense significance. Regrettably, the emergence of a novel leaf wilt in October 2017 has cast a pall over its production, leading to detrimental impacts on both yield and quality. By meticulous single-conidial isolation, this new pathogen was successfully extracted from ten diseased leaves. Subsequent confirmation of pathogenicity was achieved via the meticulous execution of Koch's postulates. In pursuit of accurate identification, morphological data were harmonized with a concatenated sequence analysis of the rDNA internal transcribed spacer (ITS), β-tubulin (TUB), and translation elongation factor 1 (TEF) regions. This rigorous approach unveiled the pathogen as an entirely novelNeopestalotiopsis species, warranting the nomenclature Neopestalotiopsis strain CP1. The optimum pH of conidial germination was between 5.0 and 5.5. Among the 665 different metabolites of the Neopestalotiopsis strain CP1, 60 carbon sources, 35 nitrogen sources, 4 phosphate sources, 8 sulfur sources, and 1 biometabolic pathway, effectively promoted the growth and development of conidia. The optimum pH of conidial germination was between 5.0 and 5.5. Among the 665 different metabolites of the Neopestalotiopsis strain CP1, 60 carbon sources, 35 nitrogen sources, 4 phosphate sources, 8 sulfur sources, and 1 biometabolic pathway, effectively promoted the growth and development of conidia. The ramifications of this pathogen's definitive identification and ongoing surveillance cannot be overstated, signifying a pivotal alert to zedoary turmeric cultivators in confronting this newfound peril.

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Determination of the absolute configurations and anti-angiogenic activities of new diarylheptanoid glucosides from Curcuma phaeocaulis

Li,

Peng,

et al. 2024

Arabian Journal of Chemistry

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Ethanol extracts from twelve Curcuma species rhizomes in China: Antimicrobial, antioxidative and anti-inflammatory activities

Cited by 7 publications

References 16 publications

Anti-Inflammatory and Antioxidant Chinese Herbal Medicines: Links between Traditional Characters and the Skin Lipoperoxidation “Western” Model

Anti-Inflammatory and Antioxidant Chinese Herbal Medicines: Links between Traditional Characters and the Skin Lipoperoxidation “Western” Model

The Identification and Characterization of a New Species, Neopestalotiopsis Strain CP1, a Pathogen Causing Leaf Blight on Curcuma phaeocaulis in Guangxi, China

Determination of the absolute configurations and anti-angiogenic activities of new diarylheptanoid glucosides from Curcuma phaeocaulis

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