Estudo da expressão imunoistoquímica da proteína galectina-3 associada à -catenina e ciclina D1 em carcinoma adenóide cístico e adenocarcinoma polimorfo de baixo grau de malignidade de glândulas salivares
Abstract:Salivary gland tumors are uncommon and the mechanism by which malignant tumors progresses is still undefined. In a previous study it was shown that galectin-3 is expressed in malignant salivary gland neoplasms as adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma. Galectin-3 is a multifunctional protein of a group of galactoside-binding lectins expressed in a variety of normal cells, but also has been implicated in tumor progression of some malignancies as thyroid, prostate and gastric cancers.… Show more
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