Estudio molecular de los polimorfismos comunes del gen apoE asociados con disbetalipoproteinemia familiar y la enfermedad de Alzheimer de inicio tardío

Abstract

The objectives of this report were to evaluate apoE determination by qPCR in the diagnosis of familial dysbetalipoproteinemia; and its integration as a predictive factor within a prognostic model with the aim of establishing the risk of late-onset Alzheimer’s disease. This report aims to evaluate the use of this technology in the described context, and its comparison with other genetic (and/or phenotypic, in the case of familial dysbetalipoproteinemia) techniques.