Estudio comparativo de los hallazgos clínicos en la enfermedad orbitaria asociada a IgG4 con afectación unilateral vs. bilateral

Coloma-González, I.; Ceriotto, A.; Flores-Preciado, J.; Corredor-Casas, Sonia; Salcedo-Casillas, Guillermo

doi:10.1016/j.oftal.2015.02.018

Cited by 2 publications

(1 citation statement)

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“…Although knowledge regarding IgG4RD has increased over the last decade, diagnostic challenges remain. The variability of clinical presentation due to the wide range of potentially affected organs in IgG4RD makes the diagnosis difficult—sometimes taking years to establish [2] . This report is intended to increase awareness of IgG4RD as a process that may present as isolated submandibular gland swelling in a child.…”

Section: Introductionmentioning

confidence: 99%

IgG4-related disease in an adolescent with radiologic-pathologic correlation

Silva

Hoffman

Policeni

et al. 2017

Radiology Case Reports

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Immunoglobulin G4–related disease (IgG4RD) is an immune-mediated condition characterized by lymphoplasmacytic infiltrates and fibrosis of affected organs. IgG4RD may affect many different organs either individually or together in a multiorgan condition and, thus, incorporates a wide range of fibroinflammatory phenotypes with shared pathologic features. Although IgG4RD most commonly occurs in late adulthood, it may affect children and adolescents. Only one case of IgG4RD presenting as isolated submandibular gland involvement has been reported in the pediatric population. Radiographic features of IgG4RD are often nonspecific making diagnosis challenging, but it is important for radiologists to be familiar with this diseased as its inclusion the differential for diffuse salivary enlargement may be the first step in making an accurate diagnosis. Here, we report a case of a child presenting with bilateral submandibular gland swelling to increase awareness of this condition in the pediatric population.This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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Section: Introductionmentioning

confidence: 99%