Estudio clinicoepidemiológico de la bronquiolitis aguda

García, Hugo; García, F.M. García; Alonso, J.E. Fernández

doi:10.1016/s1695-4033(00)77493-5

Cited by 6 publications

(1 citation statement)

References 24 publications

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“…[ 3 ] In Spain, the incidence of bronchiolitis is estimated at 7%, and hospital admissions is estimated at 1.79% annually in children younger than 2 years. [ 4 ] However, in low/middle-income countries, the data on admissions of children with severe bronchiolitis and their outcomes are seldom up to date.…”

Section: Introductionmentioning

confidence: 99%

Risk factors for severe bronchiolitis caused by respiratory virus infections among Mexican children in an emergency department

Robledo-Aceves¹,

Moreno-Peregrina²,

Velarde-Rivera

et al. 2018

Medicine

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Severe bronchiolitis is the most common reason for hospitalization among children younger than 2 years. This study analyzed the prevalence of community-acquired respiratory virus infection and the risk factors for hospitalization of Mexican children with severe bronchiolitis treated in an Emergency department.This retrospective study included 134 children 2 years or younger with severe viral bronchiolitis, and 134 healthy age-matched controls. The study period was September 2012 to January 2015. We determined the viral etiology and coinfections with multiple viruses and compared the risk factors detected in children with severe viral bronchiolitis with those in the control group.A total of 153 respiratory viruses in these 134 patients, single or mixed infections, were identified: respiratory syncytial virus (RSV) type A or B was the most frequently detected (23.6% and 17.6%, respectively), followed by rhinovirus (RV; 16.3%) and parainfluenza virus (PIV) type 3 (12.4%). Coinfections of 2 respiratory viruses were found in 14.2% of cases; all cases had either RSV type A or B with another virus, the most common being parainfluenza virus or rhinovirus. Exposure to cigarette smoking was independently associated with hospitalization for severe bronchiolitis (OR, 3.5; 95% CI, 1.99–6.18; P = .0001), and having completed the vaccination schedule for their age was a protective factor against adverse outcome (OR, 0.55; 95% CI, 0.35–0.87; P = .010).RSV is a common infection among young children with severe bronchiolitis; thus, developing a vaccine against RSV is essential. Campaigns to reinforce the importance of avoiding childhood exposure to cigarette smoke are also needed.

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Section: Introductionmentioning

confidence: 99%

Risk factors for severe bronchiolitis caused by respiratory virus infections among Mexican children in an emergency department

Robledo-Aceves¹,

Moreno-Peregrina²,

Velarde-Rivera

et al. 2018

Medicine

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Conferencia de Consenso sobre bronquiolitis aguda (VI): pronóstico en la bronquiolitis aguda. Revisión de la evidencia científica

Sangrador

2010

Anales de Pediatría

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We present a review of the evidence on prognosis of acute bronchiolitis, risk factors for severe forms, symptom or severity scores and risk of post-bronchiolitis asthma. Documented risk factors of long stay or PICU admission in hospitalized patients are: bronchopulmonary dysplasia and/or chronic lung disease, prematurity, congenital heart disease and age less than 3 months. Other less well documented risk factors are: tobacco exposure, history of neonatal mechanical ventilation, breastfeeding for less than 4 months, viral co-infection and other chronic diseases. There are several markers of severity: toxic appearance, tachypnea, hypoxia, atelectasis or infiltrate on chest radiograph, increased breathing effort, signs of dehydration, tachycardia and fever. Although we have some predictive models of severity, none has shown sufficient predictive validity to recommend its use in clinical practice. While there are different symptom or severity scores, none has proven to be valid or accurate enough to recommend their preferable application in clinical practice. There seems to be a consistent and strong association between admission due to bronchiolitis and recurrent episodes of wheezing in the first five years of life. However it is unclear whether this association continues in subsequent years, as there are discordant data on the association between bronchiolitis and asthma.

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