Estructura genética poblacional del gen lactoferrina bovino en vacas Holstein del departamento de Antioquia

C, Nancy Rodríguez; H, Albeiro López; Z, Julián Echeverri

doi:10.21897/rmvz.198

Cited by 5 publications

(8 citation statements)

References 16 publications

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“…This could explain the genetic differentiation found among subpopulations in the department of Antioquia; although there is genetic flux between them, it has not been sufficient to homogenize the allelic frequencies, although it could be thought that the populations are in a process of homogenization. In other studies (4,19), the number of migrants that has been reported is much greater than what was found in this investigation. Based on a SNP, the growth hormone gene (bGH) was reported for the Holstein population in Antioquia at Nm=36 (4), while based on the SNP of the lactoferrine gene (LTF), Nm=25 has been reported for the same population (19).…”

Section: Discussioncontrasting

confidence: 79%

“…Esto podría explicar la diferenciación genética encontrada entre las subpoblaciones del departamento de Antioquia; aunque existe flujo genético entre ellas este no ha sido suficiente para homogenizar las frecuencias alélicas, sin embargo se puede pensar que las poblaciones se encuentran en un proceso homogenización. En otros estudios (4,19) se ha reportado un número de migrantes mucho mayor al encontrado en esta investigación. Con base en un SNP del gen de hormona de crecimiento (bGH) se reportó para la población Holstein de Antioquia un Nm=36 (4), mientras que con base en un SNP del gen de lactoferrina (LTF) se ha reportado un Nm=25 para la misma población (19).…”

Section: Discussionunclassified

“…En otros estudios (4,19) se ha reportado un número de migrantes mucho mayor al encontrado en esta investigación. Con base en un SNP del gen de hormona de crecimiento (bGH) se reportó para la población Holstein de Antioquia un Nm=36 (4), mientras que con base en un SNP del gen de lactoferrina (LTF) se ha reportado un Nm=25 para la misma población (19). Este alto valor puede deberse a la implementación de la inseminación artificial que permite eliminar las barreras geográficas y aumentar el flujo genético entre las poblaciones (4,19).…”

Section: Discussionunclassified

“…Based on a SNP, the growth hormone gene (bGH) was reported for the Holstein population in Antioquia at Nm=36 (4), while based on the SNP of the lactoferrine gene (LTF), Nm=25 has been reported for the same population (19). This high value could be due to implementing artificial insemination that eliminates geographic barriers and increases the genetic flux between populations (4,19).…”

Section: Discussionmentioning

confidence: 99%

“…El menor número de SPC fue para los individuos GGTT y el mayor para los AGAT, pero no se puede afirmar que alguno de los alelos analizados presente una tendencia a aumentar o disminuir el valor de esta característica. chromosomes, 2 and 11 respectively, these have a maximum recombinant rate, that is, 0.5, confirming their independent segregation according to the second law of Mendel (19).…”

Section: Discussionunclassified

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Genetic structure of Antioquia Holstein from two SNPs and association with dairy traits

2015

Rev MVZ Córdoba

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Objective. Analyze the structure and genetic differentiation of a population of Antioquia Holstein cows from the polymorphisms A192G of INHA and A-320T of FSHR, and explore the association of the genotypic combinations with milk traits. Materials and methods. 1240 lactations of 356 animals from 9 herds in 6 municipalities of Antioquia were analyzed. Genotyping was performed by PCR-RFLP. Structure and genetic diversity parameters were determined using GenAlex software. The association of genotypes combinations with productive and reproductive traits was explored through a linear mixed model. Results. SNP A192G showed a frequency of 0.534 and 0.466 for A and G alleles respectively and SNP A-320T had a frequency of 0.660 far A allele and 0.339 for T allele, this way the population is in HWE. The FST, FIS and FIT values were 0.059, 0.285 and 0.328 respectively indicating a moderate genetic differentiation between subpopulations. The A-320T SNP showed significant effect on milk yield. Fat and protein percentage, calving interval and services per conception were not affected by these polymorphisms or their interaction. Conclusions. Phenotypic selection made on this population has not been strong enough to generate noticeable changes in allele frequencies of these polymorphisms or deviations from Hardy-Weinberg equilibrium. The interaction of these polymorphisms has no significant effect on the characteristics of zootechnical interest, so its use in programs of molecular marker assisted selection is not recommended.

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Section: Discussioncontrasting

confidence: 79%

Section: Discussionunclassified

Section: Discussionmentioning

confidence: 99%

Section: Discussionunclassified

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Genetic structure of Antioquia Holstein from two SNPs and association with dairy traits

2015

Rev MVZ Córdoba

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Diversidad Genética de Palomas Domésticas (Columba livia) en Lorica, Colombia, Utilizando Genes que Codifican la Coloración del Plumaje

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Vargas

2016

Rev. investig. vet. Perú

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RESUMENEl objetivo de este trabajo fue evaluar la diversidad genética de las poblaciones de palomas domésticas (Columba livia) en Lorica, Colombia, utilizando genes que codifican la coloración y diseño del plumaje. Se realizaron muestreos aleatorios en seis colonias entre noviembre y diciembre de 2015. Mediante excursiones urbanas, observación directa y registros fotográficos se estudiaron 356 palomas. Se utilizaron los marcadores autosómicos que codifican la coloración y diseño del plumaje: Grizzle (G), Spread (S), Checker (C), y el locus ligado al sexo Ash-Red (B). Los parámetros genéticos de frecuencia alélica, diversidad genética, equilibrio Hardy-Weinberg y estructura poblacional fueron calculados a través del programa PopGene 1.31, la estructura genética y la distancia genética mediante el programa FSTAT v. 2.9.3.2, y el dendrograma se realizó con el programa MEGA 5. Los marcadores Spread y Checker fueron los de mayor frecuencia, mientras el marcador Ash-Red presentó los valores más bajos. Se obtuvo escasa diferenciación genética entre las poblaciones y un elevado flujo génico, por lo que se asume ausencia de consanguinidad. Además, se observó un exceso de heterocigotos y ausencia de equilibrio Hardy-Weinberg, y se evidenció posible selección natural para el marcador Spread.Palabras clave: frecuencias alélicas, diversidad genética, flujo génico, equilibrio HardyWeinberg

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Association of the bovine growth hormone gene with Holstein cattle reproductive parameters

2014

Rev MVZ Córdoba

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Objective. To determine the association of intron 3 polymorphism of the bovine growth hormone (BGH) gene, with age at first service, first birth, first postpartum service and second birth in a population of Holstein cows in the state of Antioquia. Materials and methods. The study was conducted on 408 Holstein cows in 8 herds. Genotyping was performed using PCR-RFLP technique with DNA extracted from peripheral blood by the salting out technique. The Phenotypic information used was collected for 4 years, from a dairy production control program. To determine the association between characteristics and gene polymorphism, parametric statistical analyzes were performed as generalized linear models and linear regression analysis. Results. Allele frequency (positive) was 0.91 and was 0.09 for (negative) allele. Genotypic frequencies were 0.77, 0.2 and 0.03 for (positive/positive), (positive/negative) and (negative/negative) respectively. There were significant differences between the mean of age at first service, age at first birth, age at first postpartum service and age at second birth. For all of the (negative/negative) genotype characteristics there were greater ages for each event. Conclusions. These results suggest that intron-3 polymorphism of the BGH gene is associated with reproductive traits, facilitating the selection of individuals with favorable genotypes for use in breeding programs.

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Estructura genética poblacional del gen lactoferrina bovino en vacas Holstein del departamento de Antioquia

Cited by 5 publications

References 16 publications

Genetic structure of Antioquia Holstein from two SNPs and association with dairy traits

Genetic structure of Antioquia Holstein from two SNPs and association with dairy traits

Diversidad Genética de Palomas Domésticas (Columba livia) en Lorica, Colombia, Utilizando Genes que Codifican la Coloración del Plumaje

Association of the bovine growth hormone gene with Holstein cattle reproductive parameters

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