Abstract:Objective: Decreasing in reproductive capacity has been observed in jaundiced female rats. The animals with hyperbilirubinemia present early sexual maturation, late ovulation, reduced number of corpora lutea and precocious vaginal opening. The interaction with toxic agents leads to abnormal development of the embryos. The objective is to investigate the influence of jaundice on estrous cycle, fertility, ovaries and fetus development.Methods: 66 female rats were divided into two groups (n=33): group 1 -ligature… Show more
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