Estrogenicity and intersex in juvenile rainbow trout (Oncorhynchus mykiss) exposed to Pine/Eucalyptus pulp and paper production effluent in Chile

Chiang, Gustavo; Barra, Ricardo; Díaz-Jaramillo, Mauricio; Rivas, Meyling; Bahamonde, Paulina; Munkittrick, Kelly R.

doi:10.1016/j.aquatox.2015.04.025

Cited by 29 publications

(25 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The present results indicate that all extracts from all pulp mill effluents from pulp‐producing countries are estrogenic in juvenile trout chronically exposed to specific SPE–dichloromethane extractive fractions, reflected by increasing levels of plasma VTG irrespective of gender (Brazil > New Zealand > Canada). This is consistent with previous intraperitoneal injection studies of Chilean mills pulping eucalyptus feedstocks and recent waterborne exposure bioassays using tertiarily treated ( Eucalyptus globulus , feedstock) pulp mill effluent , suggesting that such feedstocks are sources of substances that can be modified in vivo into estrogenic compounds.…”

Section: Discussionsupporting

confidence: 91%

“…This could explain potential alterations at the population level by pulp and paper mill effluent exposure, especially in countries (e.g., Chile, Brazil) where effects-based monitoring programs are not in place. Nevertheless, estrogenicity and imposex under field semicontrolled and laboratory conditions using trout [5,8,13] and alteration at the hormonal level in native fish populations are being related to long-term reproductive changes attributable to pulp and paper mill effluent exposure in Chile [42]. The present study provides further evidence that the effects of mill effluents on fish reproduction that have been extensively documented in Canada and New Zealand would be expected to occur in Brazilian aquatic receiving environments.…”

mentioning

confidence: 56%

“…Furthermore, few estrogenic effects were observed by the in vitro yeast estrogen screening assay, and these were only observed in Brazilian mill nonpolar SPE extracts . This lack of observed estrogenic effects differs from recent studies using in situ exposures and previous studies using similar intraperitoneal injections of SPE extracted effluents where not only estrogenic effects were prevalent but also the presence of compounds capable of inducing androgen aromatization enzymes leading to a final estrogenic effect was established . The reasons for these discrepancies are unclear and need to be understood to formulate best management practices for mills that result in effluents that have minimal or no effect on fish reproduction.…”

Section: Introductionmentioning

confidence: 71%

See 2 more Smart Citations

Evaluating the potential of effluent extracts from pulp and paper mills in Canada, Brazil, and New Zealand to affect fish reproduction: Estrogenic effects in fish

Orrego

Milestone

Hewitt

et al. 2016

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

The authors examined the potential of pulp mill effluent from pulp-producing countries (Canada, Brazil, New Zealand) to affect fish reproduction. Specifically, the estrogenic effects in juvenile rainbow trout (Oncorhynchus mykiss) pulse-exposed to 11 different mill effluent extracts (intraperitoneal injections of solid-phase extraction-dichloromethane nonpolar fraction). The results indicated that effluent extracts were estrogenic in juvenile trout irrespective of the gender, as reflected by increasing level of plasma vitellogenin (VTG; Brazil > New Zealand > Canada). Despite the high variability observed among mills, differences in VTG levels were related to the type of mill process (kraft > elementary chlorine-free kraft > thermomechanical pulping). Moreover, effluent treatments did not appear to significantly decrease VTG induction. A consistent estrogenic effect was observed in those mills that process a combination of feedstocks (softwood and hardwood), with the highest increase in VTG related to eucalyptus feedstock. The results demonstrate significant estrogenic effects of pulp mill effluents on chronically exposed juvenile trout, suggesting that in vivo metabolic activation of precursors is necessary to cause the observed increases in VTG levels. This molecular estrogenic response provides a useful starting point for predicting population-level impacts through the adverse outcome pathway methodology. Environ Toxicol Chem 2017;36:1547-1555. © 2016 SETAC.

show abstract

Section: Discussionsupporting

confidence: 91%

mentioning

confidence: 56%

Section: Introductionmentioning

confidence: 71%

See 1 more Smart Citation

Evaluating the potential of effluent extracts from pulp and paper mills in Canada, Brazil, and New Zealand to affect fish reproduction: Estrogenic effects in fish

Orrego

Milestone

Hewitt

et al. 2016

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

show abstract

“…Furthermore, the analysed exposure to contaminants in the fish muscle and bile of I. labrosus , with potential endocrine disruption effect such as phytosterols, were always below the allowed limits and being similar (López‐Rodríguez, González‐Bergonzoni, Stebniki, et al, ; Tana, ). Other studies (Chiang et al, ; Orrego et al, , , 2009,) concluded that juvenile of rainbow trout exposed to pulp and paper mill effluent in Chile showed increased gonad size, induction of maturation and estrogenicity. Since our results showed the contrasting pattern (i.e.…”

Section: Discussionmentioning

confidence: 91%

Long‐term study of the reproductive timing of the Neotropical catfish Iheringichthys labrosus (Lütken, 1874): Influence of temperature and river discharge

Vidal¹,

Mello

González‐Bergonzoni³

et al. 2020

Ecology of Freshwater Fish

View full text Add to dashboard Cite

Unravelling the effect of climate variability on species biology has been one of the main goals of ecological studies. Environmental factors such as river discharge and temperature have being proposed as triggers of reproductive cycle in fish. In temperate climates, fish reproduction is affected mainly by temperature, while is influenced by flood pulses in large tropical rivers. We evaluated the influence of temperature and river discharge as triggers of Iheringichthys labrosus’ reproduction. We studied the following reproductive variables: gonadosomatic index (GSI), hepatosomatic index (HSI) and condition factor (K). Females of I. labrosus were examined in a time series of ten years along three sites located in Lower Uruguay River at the beginning (last week of November‐first week of December, spring) and by the end of the reproductive period (middle‐end of April, autumn). Generalised linear models detected a positive effect of mean winter temperature and site on the spring mature female GSI. Site was significant in addition to the interaction between temperature and site. Moreover, the effect of winter temperature was stronger than water discharge in triggering reproductive timing of I. labrosus, contrary to the model proposed for other species in tropical systems. Additionally, a literature review suggested a latitudinal gradient on reproduction, occurring earlier and prolonged with decreasing latitude (and increasing temperature). In this study, we stated the effect of temperature on the life history in a Neotropical fish using a multifaceted approach, particularly important in the current context of global climate warming.

show abstract

“…Alternatively, the programme examined the incidence of sperm and testicular abnormalities (21). Only a few studies investigated the masculinisation of females (22,23).…”

mentioning

confidence: 99%

Occurrence of intersex in wild freshwater fish in Slovenian rivers: a histological evaluation

Vrecl

Jenčič

2016

Archives of Industrial Hygiene and Toxicology

View full text Add to dashboard Cite

The aim of this preliminary research was to establish if there are intersex occurrences in wild freshwater fish in Slovenian rivers and streams. In the first study we evaluated all fish species of both sexes obtained from the river Ljubljanica from its source to mouth. In the second study we focused on the rainbow trout (Oncorhynchus mykiss) and brown trout (Salmo trutta m. fario) males from 30 rivers and streams in different parts of Slovenia. The male gonads were histologically assessed for the presence of oocytes to determine the frequency and degree of intersex. Oocytes were found in the testicular tissue of a single grayling (Thymallus thymallus) and in the adipose tissue adjacent to the testis of a single common barbel (Barbus barbus), both from the Ljubljanica. Several cyst-like structures that resemble degenerated presumptive oocytes were also present in several trout testes. This preliminary report is the first of its kind in Slovenia. To gain a better insight into the intersex issue in Slovenia, we plan to regularly biomonitor freshwater pollution by histologically examining fish gonads and, if possible, by determining vitellogenin plasma levels in fish.

show abstract

Estrogenicity and intersex in juvenile rainbow trout (Oncorhynchus mykiss) exposed to Pine/Eucalyptus pulp and paper production effluent in Chile

Cited by 29 publications

References 38 publications

Evaluating the potential of effluent extracts from pulp and paper mills in Canada, Brazil, and New Zealand to affect fish reproduction: Estrogenic effects in fish

Evaluating the potential of effluent extracts from pulp and paper mills in Canada, Brazil, and New Zealand to affect fish reproduction: Estrogenic effects in fish

Long‐term study of the reproductive timing of the Neotropical catfish Iheringichthys labrosus (Lütken, 1874): Influence of temperature and river discharge

Occurrence of intersex in wild freshwater fish in Slovenian rivers: a histological evaluation

Contact Info

Product

Resources

About