Estrogen therapy affects right hemisphere functioning in postmenopausal women

Bayer, Ulrike; Hausmann, Markus

doi:10.1016/j.yhbeh.2008.10.009

Cited by 25 publications

(23 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This suggests that the right hemisphere is particularly sensitive to cycle-related changes. This is in line with previous studies suggesting that the right hemisphere is suppressed in normally cycling women during the luteal phase (e.g., Holländer et al, 2005;Sanders & Wenmoth, 1998;Rode et al, 1995) and in postmenopausal women using hormone therapy (Bayer & Hausmann, 2009a). In contrast, on the basis of their data from a visuospatial attention task, McCourt et al (1997) concluded that both the left and right hemispheres might have been nonspecifically activated luteally, and a slight functional asymmetry favoring the right hemisphere might have been promoted.…”

Section: Relationship Between Sex Hormones and Ihttsupporting

confidence: 88%

“…Bibawi, Cherry, & Hellige, 1995;Hausmann, 2005;Hausmann, Becker, Gather, & Güntürkün, 2002;Hausmann & Güntürkün, 2000;Heister, Landis, Regard, & SchroederHeister, 1989;McCourt, Mark, Radonovich, Willison, & Freeman, 1997;Mead & Hampson, 1997;Rode, Wagner, & Güntürkün, 1995;Sanders & Wenmoth,1998, Weis, Hausmann, Stoffers, & Sturm, 2008Weis, Hausmann, Stoffers, Vohn, Kellermann, & Sturm, 2011). In addition, FCAs change as a consequence of hormone therapy in postmenopausal women (Bayer & Erdmann, 2008;Bayer & Hausmann, 2009a). It is currently unclear which hemisphere is predominately sensitive to the influence of sex hormones.…”

Section: Introductionmentioning

confidence: 99%

“…It is currently unclear which hemisphere is predominately sensitive to the influence of sex hormones. Some studies suggest the left hemisphere is particularly affected by sex hormones (e.g., Bibawi et al, 1995;Hampson, 1990a;1990b), while others suggest it is the right (e.g., Bayer & Hausmann, 2009a;Sanders & Wenmoth, 1998). …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Sex hormonal modulation of interhemispheric transfer time

et al. 2013

View full text Add to dashboard Cite

The full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-prot purposes provided that:• a full bibliographic reference is made to the original source • a link is made to the metadata record in DRO • the full-text is not changed in any way The full-text must not be sold in any format or medium without the formal permission of the copyright holders.Please consult the full DRO policy for further details. 3

show abstract

Section: Relationship Between Sex Hormones and Ihttsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Sex hormonal modulation of interhemispheric transfer time

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Considering that MtFs identify with women, this is in line with evidence for estradiol enhancing right hemispheric functioning in women (Bayer & Hausmann, 2009; Hausmann, Becker, Gather, & Gunturkun, 2002; Weis et al., 2008) in regions involved in the fronto‐parietal network (Saletu et al., 2005). Even low doses of estradiol facilitate the functioning of brain regions involved in visual perception and attentional processes (Stevens, Clark, & Prestwood, 2005).…”

Section: Discussionsupporting

confidence: 81%

Male‐to‐female gender dysphoria: Gender‐specific differences in resting‐state networks

et al. 2017

View full text Add to dashboard Cite

IntroductionRecent research found gender‐related differences in resting‐state functional connectivity (rs‐FC) measured by functional magnetic resonance imaging (fMRI). To the best of our knowledge, there are no studies examining the differences in rs‐FC between men, women, and individuals who report a discrepancy between their anatomical sex and their gender identity, i.e. gender dysphoria (GD).MethodsTo address this important issue, we present the first fMRI study systematically investigating the differences in typical resting‐state networks (RSNs) and hormonal treatment effects in 26 male‐to‐female GD individuals (MtFs) compared with 19 men and 20 women.ResultsDifferences between male and female control groups were found only in the auditory RSN, whereas differences between both control groups and MtFs were found in the auditory and fronto‐parietal RSNs, including both primary sensory areas (e.g. calcarine gyrus) and higher order cognitive areas such as the middle and posterior cingulate and dorsomedial prefrontal cortex. Overall, differences in MtFs compared with men and women were more pronounced before cross‐sex hormonal treatment. Interestingly, rs‐FC between MtFs and women did not differ significantly after treatment. When comparing hormonally untreated and treated MtFs, we found differences in connectivity of the calcarine gyrus and thalamus in the context of the auditory network, as well as the inferior frontal gyrus in context of the fronto‐parietal network.ConclusionOur results provide first evidence that MtFs exhibit patterns of rs‐FC which are different from both their assigned and their aspired gender, indicating an intermediate position between the two sexes. We suggest that the present study constitutes a starting point for future research designed to clarify whether the brains of individuals with GD are more similar to their assigned or their aspired gender.

show abstract

“…As summarized recently, "Empirically, there are no other processes that have produced such reliable differences between the hemispheres as experiments on language (e.g., lexical decision) and spatial (e.g., mental rotation) tasks" (Hugdahl, 2000, p. 217). While the origins of functional hemispheric specialization (including handedness) remain to be determined (Bradshaw, 1988;Hugdahl, 2000;Ocklenburg, Beste, Arning, Peterburs, & Güntürkün, 2014) studies that assess its stability (Blumstein, Goodglass, & Tartter, 1975;Chiarello, Dronkers, & Hardyck, 1984;Teng, 1981;Voyer, 2003), short-term and longterm fluctuations (Bayer & Hausmann, 2009;Cabeza, 2002;Hausmann & Gunturkun, 2000;Mohr, Michel, et al, 2005), clinical relationships (Eyler, Pierce, & Courchesne, 2012;Grimshaw & Carmel, 2014;Mitchell & Crow, 2005) and individual difference relationships (Hausmann & Gunturkun, 1999;Mikheev, Mohr, Afanasiev, Landis, & Thut, 2002;Nicholls, Orr, & Lindell, 2005) require that its experimental assessment is reliable and valid (Voyer, 1998).…”

Section: Introductionmentioning

confidence: 99%

Stability of right visual field advantage in an international lateralized lexical decision task irrespective of participants’ sex, handedness or bilingualism

Willemin

Hausmann

Brysbaert³

et al. 2016

Laterality: Asymmetries of Body, Brain and Cognition

Self Cite

View full text Add to dashboard Cite

Additional information:Use policyThe full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-pro t purposes provided that:• a full bibliographic reference is made to the original source • a link is made to the metadata record in DRO • the full-text is not changed in any way The full-text must not be sold in any format or medium without the formal permission of the copyright holders.Please consult the full DRO policy for further details. Willemin, J., Hausmann, M., Brysbaert, M., Dael, N., Chmetz, F., Fioravera, A., Gieruc, K., Mohr, C. (2016). Stability of right visual field advantage in an international lateralized lexical decision task irrespective of participants' sex, handedness or bilingualis. AbstractIn lateralized lexical decision tasks, accuracy is higher and reaction times are faster for right visual field (RVF) than left visual field (LVF) presentations. Visual field differences are thought to demonstrate the left hemisphere's dominance for language.The use of different tasks and words between studies and languages make direct comparisons difficult. We performed a lateralized lexical decision task for which we selected 4-6 letter words that are used in three languages of Switzerland (French, German, and Italian) and English and Dutch. We accounted for the potential moderating roles of sex, handedness, and multilingualism (early acquisition versus late acquisition of at least one second language). One hundred participants were tested at a French-speaking University in Switzerland. All performed a French vocabulary knowledge task (Brysbaert, 2013). Results showed a RVF over LVF advantage (accuracy, reaction times, signal detection theory measures) for all groups, i.e. irrespective of participants' sex, handedness and how many languages they spoke. We observed, however, that enhanced vocabulary knowledge related to a right hemisphere shift in early bilinguals and a left hemisphere shift in late bilinguals. We discuss how the current observations can inform future studies suitable for the validation of the current task using an "international"vocabulary.

show abstract

Estrogen therapy affects right hemisphere functioning in postmenopausal women

Cited by 25 publications

References 58 publications

Sex hormonal modulation of interhemispheric transfer time

Sex hormonal modulation of interhemispheric transfer time

Male‐to‐female gender dysphoria: Gender‐specific differences in resting‐state networks

Stability of right visual field advantage in an international lateralized lexical decision task irrespective of participants’ sex, handedness or bilingualism

Contact Info

Product

Resources

About