“…We have studied a prepubertal boy with advanced feminization, but (5)(6)(7)(8)(9)(10); however, the level of expression of these enzymes diminishes rapidly after birth. Thus, the continued expression of the fetal levels of both the aromatase and sulfokinase enzyme activites after birth could give rise to increased estrogen formation from plasma prehormones and give rise to feminization such as that observed in this child.…”