ESTRO/EAU/EORTC recommendations on permanent seed implantation for localized prostate cancer

Ash, D.; Flynn, Anthony; Battermann, Jan J.; Reijke, Theodorous de; Lavagnini, Paulo; Blank, L.E.C.M.

doi:10.1016/s0167-8140(00)00306-6

Cited by 327 publications

(191 citation statements)

References 49 publications

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“…Patients were accepted for LDR therapy according to the recommendation of the European Society of Therapeutic Radiology and Oncology (ESTRO), the European Association of Urology (EAU) and the European Organization for Research and Treatment of Cancer (EORTC) [16]. One urologist (HB) and one radiation oncologist (MP) performed all implants.…”

Section: Methodsmentioning

confidence: 99%

Do Epidemiological Parameters in Patients with Localized Prostate Cancer have an Influence on whether a Patient is Envisaged for Surgery or Brachytherapy?

Kirschner‐Hermanns¹,

Klementz²,

Jakse³

et al. 2011

TOUNJ

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Abstract:Introduction: Only few studies comparing treatment outcome for patients with localized prostate cancer control their results for the possible confounding of demographic and clinical parameters. This fact prompted us to compare epidemiological data of patients before receiving brachytherapy (BT) to patients envisaged for radical prostatectomy (RP). Methodology:We looked at demographic and clinical data as well as standardized questionnaires for 856 patients. In a logistic regression analysis parameters proven to be significantly different in a university analysis were further analyzed.Results: Data of 676 patients (79%) could be evaluated. Patients before radical prostatectomy (RPP) scored best in physical functioning, role functioning and sexual activity. Patients planned for low-dose rate brachytherapy (LDR) indicated the biggest problems in partnership and sexuality. The health insurance status was not equally distributed. However, in a logistic regression analysis of patients envisaged for surgical treatment only age and physical functioning could be identified as independent factors that differ significantly between treatment groups (p<0.01), but not role functioning, sexual activity, status of health insurance, global health-related quality of life, level of education and mean PSA before treatment. Discussion:Comparative outcome studies for radical prostatectomy and brachytherapy ignore epidemiological differences. Our investigation demonstrate that younger age (odds ratio: 1.56) and higher scores of 'physical functioning' (odds ratio: 1.22) are strongly associated with a higher probability of receiving a surgical procedure when diagnosed with localized prostate cancer Conclusions:Comparative outcome studies for different treatment modalities have to control their data for epidemiological differences, especially for age and physical functioning.

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Section: Methodsmentioning

confidence: 99%

Do Epidemiological Parameters in Patients with Localized Prostate Cancer have an Influence on whether a Patient is Envisaged for Surgery or Brachytherapy?

Kirschner‐Hermanns¹,

Klementz²,

Jakse³

et al. 2011

TOUNJ

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“…24 There seems to be evidence to support defining biochemical failure in terms of three consecutive rises, the Phoenix criteria or even a rise above an absolute PSA. Potters et al used both the Phoenix and nadir + 2 definitions.…”

Section: Psa Post-brachytherapymentioning

confidence: 99%

“…Studies have shown that the sensitivity and specificity for the nadir + 2 definition (Phoenix) were 72 and 83 per cent, versus 51 and 81 per cent for three PSA rises. 24 …”

Section: Psa Post-brachytherapymentioning

confidence: 99%

Interpretation of PSA levels after radical therapy for prostate cancer

Goonewardene

Phull²,

Bahl³

et al. 2014

Trends Urol & Men's Health

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“…1). La ABS 8 introdujo en sus guías la sugerencia de utilizar estos sistemas de planificación en tiempo real respecto a los sistemas de planificación previa al implante y posteriormente ha sido suscrito por la GEC-ESTRO [9][10] . Es estas últimas guías se dan además algunas recomendaciones basadas en imagen tridimensional sobre las dosis a administrar al tumor y a los órganos sanos, especialmente a la uretra y el recto, ya que está en fase de estudio las dosis relacionadas con la toxicidad en otras localizaciones como el cuello vesical, los pedículos vasculonerviosos o el bulbo peneano.…”

Section: Cáncer De Próstataunclassified

Braquiterapia guiada por imagen

Villafranca

Romero

Sola

et al. 2009

Anales Sis San Navarra

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RESUMENLa braquiterapia consiste en la administración de radiación en contacto íntimo con el tumor, con una baja exposición de los tejidos sanos circundantes. Empezó a utilizarse a comienzos del siglo XX y desde entonces ha ido desarrollándose: diferentes radioisótopos, sistemas de tratamiento a distancia, programas informáticos que permiten un cálculo individualizado de la dosis.Los cambios en los últimos años dentro de la braquiterapia han afectado a dos aspectos. En primer lugar, la incorporación de las técnicas de imagen como la ecografía, la tomografía computarizada (TC) y la resonancia magnética (RM), imprescindibles para el diagnóstico y la estadificación tumoral. Su utilización mientras se realiza el implante ayuda a guiarlo y realizarlo con mayor precisión. En segundo lugar, la utilización de TC, RM y ecografía permiten mejorar la cobertura del tumor o reducir la dosis a los órganos sanos. Se utilizan dentro de sistemas de planificación inversa, que realizan el cálculo de dosis a partir de las recomendaciones de las dosis a administrar al tumor y a los órganos sanos. En estos programas de planificación es posible hacer los cálculos con mucha rapidez, teniendo en cuenta la colocación en cada momento de la fuente. Esta técnica, llamada planificación en tiempo real, empieza a mostrar ventajas en el tratamiento de los cánceres de próstata.La incorporación de las técnicas de imagen y las mejoras en los sistemas de cálculo han hecho que en la actualidad la braquiterapia juegue un papel importante en el tratamiento del cáncer de próstata, cérvix, mama, tumores de cabeza y cuello, bronquio o esófago.Palabras clave. Braquiterapia guiada por imagen. Planificación en tiempo real. Cáncer de próstata. Cáncer de mama. Cáncer de cérvix. ABSTRACTBrachytherapy consists in the administration of radiation in intimate contact with the tumour, with a low exposure of neighbouring healthy tissues. Its use began in the early XX century and it has developed since then: different radioisotopes, systems of remote treatment, computer programs making individual dose calculation possible.In recent years there have been changes affecting two aspects of brachytherapy. In the first place, the incorporation of imaging techniques such as echography, computerised tomography (CT) and magnetic resonance (MR), indispensable for diagnosis and tumoural staging. Their use when the implant is being done helps in guiding and carrying out the operation with greater precision. In the second place, the use of CT, MR and echography makes better coverage of the tumour possible, or reduces the dose to healthy organs. They are used in inverse planning systems, which carry out dose calculation on the basis of the doses to be administered to the tumour and healthy organs. In these planning programs it is possible to make calculations more rapidly, taking account of the placement of the source at each moment in time. This technique, called real-time planning, is starting to show advantages in the treatment of prostate cancer.Incorporation of imaging techni...

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ESTRO/EAU/EORTC recommendations on permanent seed implantation for localized prostate cancer

Cited by 327 publications

References 49 publications

Do Epidemiological Parameters in Patients with Localized Prostate Cancer have an Influence on whether a Patient is Envisaged for Surgery or Brachytherapy?

Do Epidemiological Parameters in Patients with Localized Prostate Cancer have an Influence on whether a Patient is Envisaged for Surgery or Brachytherapy?

Interpretation of PSA levels after radical therapy for prostate cancer

Braquiterapia guiada por imagen

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