This research aimed to verify the mental health status related to occupational factors of nursing professionals in a public hospital in the State of Goiás, Brazil. This quantitative descriptive research characterized the psychosocial aspects and mental disorders developed by the nursing team in a public hospital in Goiás. The questionnaire application occurred during August and September 2020. The study sample was composed of 15 nursing professionals of a participating hospital in Goiás. The occupational health of nurses in a hospital may involve several challenges since their work environment may change according to each company reality. Thus, the professional may work in dangerous, risky, unhealthy, refrigerated, noisy, confined, or shared locations. We then conclude the mental disorders are present in the daily life of professionals who work in a hospital environment, especially nurses, and are related to circumstances experienced within the workplace itself, leading to gradual illness among the professionals.