“…The molecular weight of thioTEPA is 189 and it was therefore expected it would be absorbed. Using a chemical method ofestimation devised by Raine (1962), it was shown that thioTEPA was absorbed from the bladder. In 2 patients first treated with this technique, a small total dose of 30 mg of thioTEPA in 100 ml sterile water was used, and the absorption of the drug estimated chemically.…”