Estimation of the relative liver perfusion using two methods of radionuclide angiography in the patients with hemodynamic disorders in the portal system

Artiko, Vera; Šobić-Šaranović, Dragana; Pavlović, Smiljana; Perisić-Savić, M; Stojković, Mirjana; Radoman, Irena B; Knežević, S; Vlajković, Marina; Obradović, Vladimir

doi:10.2298/aci0801011a

Cited by 2 publications

(2 citation statements)

References 12 publications

(20 reference statements)

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“…Moreover, differential diagnosis of these liver lesions is difficult, even with clinical, biochemical data, and imaging techniques [4][5][6][7][8][9]. Recently Doppler sonography has been used to characterize focal hepatic lesions with a higher diagnostic confidence [10].…”

Section: Introductionmentioning

confidence: 99%

Diagnostic accuracy of color Doppler in diagnosis of Hepatocellular carcinoma taking histopathology as gold standard

Ali¹,

Saba²,

Zaidi³

et al. 2013

JBiSE

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Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world and the third most common cause of cancer mortality. Despite the high numbers of patients diagnosed worldwide, HCC continues to pose challenging clinical problems. Good-quality ultra sound with careful evaluation of the entire liver can be a screening examination for HCC in patients at risk. The aim of the study was to determine the diagnostic accuracy of the Doppler sonography for differentiation of hepatocellular carcinoma (HCC) from other focal liver lesions by taking histopathology as a gold standard. It was a cross-sectional survey, conducted in the Department of Diagnostic Radiology, King Edward Medical University/Mayo Hospital, Lahore in one year from 13-12-2010 to 12-12-2011. A total of 70 patients were included in this study with focal lesions on ultrasound are included while pregnant patients are excluded. After evaluating by Doppler sonography and doing core biopsy, the patients were sent to the Department of Pathology, Mayo Hospital for histopathological examination. Histopathology was assessed for confirmation of positive and negative cases. Mean age of the patients was 60.9 ± 4.7 years. Out of 70 patients, 47 patients (67.1%) were male while remaining 23 patients (32.9%) were female. On Doppler sonography 37 cases were positive for hepatocellular carcinoma and 33 cases were negative while 36 cases were positive and 34 negative on histopathology. On Doppler sonography, sensitivity (94.4%), specificity (91.1%), diagnostic accuracy (92.8%), positive predictive value (91.8%) and negative predictive value was 93.9%. We concluded that Doppler sonography is a useful method for differen-tiation of Hepatocellular carcinoma from other focal liver lesions, detection and characterization of hepatocellular carcinoma.

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Section: Introductionmentioning

confidence: 99%

Diagnostic accuracy of color Doppler in diagnosis of Hepatocellular carcinoma taking histopathology as gold standard

Ali¹,

Saba²,

Zaidi³

et al. 2013

JBiSE

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“…The use of Color Doppler (CD) in the investigation of vascularisation of focal lesions in the liver brings about new possibilities in differential diagnostics of focal hepatic lesions [2] . In the pre-evaluation and diagnosis of patients with liver tumors, after ultrasonography and Doppler-US and contrast enhanced ultrasonography (CEUS), significant nuclear medicine methods are used: radiocolloids, blood pool, hepatobiliary scintigraphy, angioscintigraphy with radiolabeled microspheres and "first pass" radionuclide angiography [3][4][5][6] . These methods precede selective angiography and other invasive methods.…”

Section: Introductionmentioning

confidence: 99%

Color Doppler sonography and angioscintigraphy in hepatic Hodgkin’s lymphoma

Stojković¹,

Artiko²,

Radoman³

et al. 2009

WJG

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AIM:To estimate the characteristics of Color Doppler findings and the results of hepatic radionuclide angiography (HRA) in secondary Hodgkin's hepatic lymphoma. METHODS:The research included patients with a diagnosis of Hodgkin's lymphoma with metastatic focal lesions in the liver and controls. Morphologic characteristics of focal liver lesions and hemodynamic parameters were examined by pulsed and Color Doppler in the portal, hepatic and splenic veins were examined. Hepatic perfusion index (HPI) estimated by HRA was calculated. RESULTS:In the majority of patients, hepatomegaly was observed. Lesions were mostly hypoechoic and mixed, solitary or multiple. Some of the patients presented with dilated splenic veins and hepatofugal blood flow. A pulse wave was registered in the centre and at the margins of lymphoma. The average velocity of the pulse wave was higher at the margins (P > 0.05). A continuous venous wave was found only at the margins of lymphoma. There was no linear correlation between lymphoma size and velocity of pulse and continuous wave (r = 390, P < 0.01). HPI was significantly lower in patients with lymphomas than in controls (P < 0.05), pointing out increased arterial perfusion in comparison to portal perfusion. CONCLUSION:Color Doppler ultrasonography is a sensitive method for the detection of neovascularization in Hodgkin's hepatic lymphoma and estimation of its intensity. Hepatic radionuclide angiography can additionally help in the assesment of vascularisation of liver lesions.

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Estimation of the relative liver perfusion using two methods of radionuclide angiography in the patients with hemodynamic disorders in the portal system

Cited by 2 publications

References 12 publications

Diagnostic accuracy of color Doppler in diagnosis of Hepatocellular carcinoma taking histopathology as gold standard

Diagnostic accuracy of color Doppler in diagnosis of Hepatocellular carcinoma taking histopathology as gold standard

Color Doppler sonography and angioscintigraphy in hepatic Hodgkin’s lymphoma

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