Estimation of the relative biological effectiveness for double strand break induction of clinical kilovoltage beams using Monte Carlo simulations
Oran McElligott,
Mihails Nikandrovs,
Patrick McCavana
et al.
Abstract:BackgroundThe Relative Biological Effectiveness (RBE) of kilovoltage photon beams has been previously investigated in vitro and in silico using analytical methods. The estimated values range from 1.03 to 1.82 depending on the methodology and beam energies examined.PurposeThe focus of this work was to independently estimate RBE values for a range of clinically used kilovoltage beams (70–200 kVp) while investigating the suitability of using TOPAS‐nBio for this task.MethodsPreviously validated spectra of clinical… Show more
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