Estimation of the conductance of channels for rarefied gas flow by means of an optical analogue

Carpenter, L. G.; Watts, M J

doi:10.1088/0022-3727/9/18/513

Cited by 2 publications

(1 citation statement)

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“…Because outbreaks of food poisoning caused by staphylococcal contamination of food are common [1] and most frequently involve staphylococcal enterotoxin A (SEA)-producing strains [2], there have been several studies of SEA synthesis. These experiments were largely conducted in batch cultures and indicated that toxin accumulation was apparently growth related [5], occurring mainly dur-248 ing the exponential phase of growth [6]• These studies did not identify any particular medium component or other culture condition that specifically controlled toxin synthesis [7], except for a repressive effect of glucose, which has also been reported for synthesis of enterotoxin B (SEB) and enterotoxins C [8]. The present work investigates SEA synthesis and location in chemostat culture using a defined medium•…”

Section: Introductionmentioning

confidence: 99%

Glucose control of staphylococcal enterotoxin A synthesis and location is mediated by cyclic AMP

Hallis

Thurston

Mason

1991

FEMS Microbiology Letters

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The regulation of staphylococcal enterotoxin A (SEA) synthesis in a defined medium was studied using continuous culture techniques. SEA production was repressed by glucose and repression could be overcome by addition of exogenous cyclic AMP. As well as this classical catabolite repression control, addition of glucose to de‐repressed steady‐state cultures resulted in rapid disappearance of toxin from the medium (also mediated by loss of cyclic AMP). When the toxin dissappeared from the medium, it was taken up again by the bacteria without apparent modification.

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