Estimation of Standardized Ileal Digestible Lysine Requirement of Starting Broiler Chicks Fed Soybean-and Cottonseed Meal-Based Diets

2014

Poultry Science

Self Cite

The optimization algorithm of a model may have significant effects on the final optimal values of nutrient requirements in poultry enterprises. In poultry nutrition, the optimal values of dietary essential nutrients are very important for feed formulation to optimize profit through minimizing feed cost and maximizing bird performance. This study was conducted to introduce a novel multi-objective algorithm, desirability function, for optimization the bird response models based on response surface methodology (RSM) and artificial neural network (ANN). The growth databases on the central composite design (CCD) were used to construct the RSM and ANN models and optimal values for 3 essential amino acids including lysine, methionine, and threonine in broiler chicks have been reevaluated using the desirable function in both analytical approaches from 3 to 16 d of age. Multi-objective optimization results showed that the most desirable function was obtained for ANN-based model (D = 0.99) where the optimal levels of digestible lysine (dLys), digestible methionine (dMet), and digestible threonine (dThr) for maximum desirability were 13.2, 5.0, and 8.3 g/kg of diet, respectively. However, the optimal levels of dLys, dMet, and dThr in the RSM-based model were estimated at 11.2, 5.4, and 7.6 g/kg of diet, respectively. This research documented that the application of ANN in the broiler chicken model along with a multi-objective optimization algorithm such as desirability function could be a useful tool for optimization of dietary amino acids in fractional factorial experiments, in which the use of the global desirability function may be able to overcome the underestimations of dietary amino acids resulting from the RSM model.

Section: Discussionsupporting

confidence: 52%

Section: Introductionmentioning

confidence: 98%

Optimization of response surface and neural network models in conjugation with desirability function for estimation of nutritional needs of methionine, lysine, and threonine in broiler chickens

2014

Poultry Science

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“…The continuous data need to be tted by regression models either with linear or quadratic patterns. Among different mathematical models, broken line models are the most prevalent models for determination of nutrient requirements in mammals and poultry [6][7][8][9][10][11][12][13][14] . In general, the broken line models consisted of one or two slope sections and each section may follow the linear and/or quadratic manners in ascending and/or descending orders 6-8, 15 .…”

Section: Introductionmentioning

confidence: 99%

Physiological and statistical aspects of immunoregulatory and antioxidant properties of tryptophan

Pajouhanfar

Ghazaghi

2022

Preprint

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Tryptophan (Trp) is the third or fourth limiting amino acid for the most poultry species fed on corn-soybean meal-diets, playing an important role in the profile of the blood biochemical variables, humoral immunity, and antioxidant capacity. A dose-response assay was carried out to investigate the effects of graded levels of dietary Trp on blood variables, immunity and meat quality in quail chicks during the last two weeks of growing period. A total of 420, 21-day-old quail chicks were randomly distributed across the seven experimental groups (i.e., 2.12, 2.25, 2.38, 2.51, 2.64, 2.77, and 2.90 g Trp /kg of diet) with 4 pen replicates of 15 birds each. Blood variables including uric acid (UA), albumin (ALB), and triglycerides (TG) responded inversely to increasing dietary Trp (P < 0.001). Blood concentration of aspartate aminotransferase (AST), relative weight of bursa of Fabricius (BF), immunoglobulin G (IgG), water holding capacity (WHC), and antigen production against the sheep red blood cells (SRBC) increased with increases in dietary Trp (P < 0.001). In contrast, the concentration of malondialdehyde (MDA) and drip loss in meat samples decreased with increasing dietary Trp (P < 0.001). The best models for determination of optimal dietary Trp were selected based on a statistical merit called model accuracy index (δ). The optimal amounts of dietary Trp for optimizing ALP, UA, total protein (TP), TG, SRBC, IgG, BF, drip loss, WHC, and MDA were estimated at 2.347, 2.371, 2,372, 2.485, 2,691, 2.738, 2.306, 2.359, 2.247, and 2.500 g/kg of diet, respectively. Principal component analysis showed that UA, TG, IgG, and drip loss had the higher association with dietary Trp compared to the rest responses. Taking into account of high δ and eigenvalues for fitted bird responses, the more reliable estimation of optimal Trp for optimization of studied responses in quail chicks would be 2.738 g Trp/kg of diet, which was significantly higher than that recommended for the quail performance.

“…EAA) under different conditions, the specific ratio of each nutrient to dietary AME may be considered as an efficient practice. Usually, experiments dealing with determination of AA requirements were based on single titration of a specific AA and obtaining breakpoint as ‘ requirement ’ point without taking into account complex relationships between AAs and other nutritional factors such as AME (Baker and Han, ; Han and Baker, ; Baker et al., ; Dozier et al., ; Mehri et al., ,b, ; Zaboli et al., ). It has been reported that the optimal ratios of lysine to AME (Lys: AME) might be needed for optimization of growth performance of broiler chickens in different phases of growth (Ajinomoto, ), where more lean carcass could be obtained with higher ratio of Lys: AME.…”

Section: Introductionmentioning

confidence: 99%

A simple estimation of ideal profile of essential amino acids and metabolizable energy for growing Japanese quail

Animal Physiology Nutrition

Ghazaghi

Kasmani

et al. 2015

An experiment was conducted to determine apparent metabolizable energy (AME) and amino acid requirements of growing Japanese quail based on ideal protein concept using artificial neural network and desirability function (D-ANN). Seven-day-old quail chicks were assigned to nine experimental diets based on central composite design (CCD) containing five levels of AME (2809-3091 kcal/kg) and CP (19-24.8% of diet). The ratio of lysine (Lys) to CP was set at 0.053 among all treatments, and remaining essential amino acids (EAA) were adjusted to Lys. The experimental data of CCD were fitted to D-ANN model to compute the optimal values for independent variables. The optimal values of inputs including AME, CP, digestible Lys (dLys), methionine (dMet), total sulphur amino acids (dTSAA), threonine (dThr), tryptophan (dTrp), isoleucine (dIle), valine (dVal) and arginine (dArg) for maximizing gain and minimizing feed conversion ratio were estimated at 2865 kcal/kg, 25, 1.32, 0.55, 0.88, 0.84, 0.20, 0.75, 1.04 and 1.45% of diet, respectively, with D (desirability function) = 0.94. The corresponding optimal amounts of amino acids based on total amino acids were 1.42, 0.59, 0.95, 0.90, 0.22, 0.81, 1.12 and 1.56% of diet respectively. The ideal pattern of essential amino acids to Lys was as follows: dMet: dLys = 0.42, dTSAA: dLys = 0.67, dThr: dLys = 0.64, dTrp: dLys = 0.15, dIle: dLys = 0.57, dVal: dLys = 0.79 and dArg: dLys = 1.09. The results of this study showed that amino acid requirements of modern quails might be higher than those reported by NRC.