Estimation of serum and red cell folate by a simple radiometric technique

Mincey, E.K.; Wilcox, Eileen; Morrison, Robert E.

doi:10.1016/s0009-9120(73)80036-0

Cited by 14 publications

(1 citation statement)

References 7 publications

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“…The plasma and red cell folate levels were measured by radiometric assay using the method of Rothenberg et al (1972) as modified by Mincey et al (1973) and subsequently by Bagni et a1 (1975). Following a 12 h overnight fast, the blood specimens were drawn, between 8 and 9 a.m., by venipuncture without tourniquet, from subjects who had been sitting for 5 min.…”

Section: Methodsmentioning

confidence: 99%

Folic Acid Deficiency in β‐Thalassaemia Heterozygotes

Castaldi

Bagni

Trotta

et al. 1983

Scandinavian Journal of Haematology

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Plasma and red cell folate mean contents have been found to be significantly lower in 41 symptom-free P-thalassaemia heterozygotes than in 21 controls. Such decreases must be considered as effects of an increased folate utilization caused by the enhanced total, both effective and ineffective, erythropoiesis. Since no close correlation has been found between packed cell volume and plasma or red blood cell folate levels, it seems that in 'healthy' P-thalassaemia subjects, the degree of anaemia is not influenced by folate body reserves. However, the frequent finding of reduced red cell folate contents suggests that further folate imbalance might lead to clinically significant degrees of folate deficiency.

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Section: Methodsmentioning

confidence: 99%