Estimation of retention times of homologous series in temperature programmed gas chromatography

Abstract

SummaryIt is shown how to estimate the retention times of homologous series members in linear temperature programmed gas chromatography with the aid of a spreadsheet. Both the ease of estimation and the accuracy of the estimation depend on whether the homologue is eluted during the rising portion of the temperature program or the hold time at the end, and also on whether the homologous series is eluted from one injection or a number of injections. When all members of the series elute in the one chromatographic run the percentage standard deviation of the predicted retention times from the experimental retention times is 0.1. When members of the series elute in different chromatographic runs, the percentage standard deviation of predicted times from experimental times is 0.6, compared with an experimental percentage standard deviation for replicates of 0.5.

Rapid Temperature-Programmed Separation and Retention Prediction on a Novel Packed-Capillary Column in Gas Chromatography

“…Downsizing of the packed column also permits the use of the resulting miniaturized packed column in a modern capillary GC system without any special modification to the instruments, although the compatibility of the packed column to the temperature-programmed operation should be considered as typically reported in several publications dealing with the theoretical prediction of the retention time for separation with temperature programming. [13][14][15][16][17][18][19][20][21] In contrast to a number of papers for a theoretical prediction of the retention in GC, a comprehensive comparison of the compatibility of packed columns having different internal diameters to a rapid temperature program in a modern GC system had been quite limited. [21][22][23] In this work, novel packed-capillary columns were developed with a thin-wall capillary of stainless-steel, and the compatibility to a fast temperature-programmed separation was studied on the basis of a theoretical prediction of the retention by a numerical-integration method.…”

Trace Metal Speciation with ICP‐MS Detection

“…Several reviews and books have been published on the theory of GC, which will not be treated here in its entirety. 166,167 In GC, we distinguish between separation on packed columns and on capillary columns. Briefly, packed columns have a large inner diameter (2-6 mm) and are filled with an inert support coated with the liquid stationary phase, while capillary columns are open tubes with small inner diameter, the liquid stationary phase coating the inner wall.…”