Estimation of reduced life expectancy from serious occupational injuries in Taiwan

Ho, Ja‐an Annie; Hwang, Jing‐Shiang; Wang, Jung‐Der

doi:10.1016/j.aap.2006.03.007

Cited by 15 publications

(5 citation statements)

References 24 publications

(18 reference statements)

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“…The validity of our extrapolation for long-term survival using this statistics package has been validated in previously published studies. [13][14][15] …”

Section: Estimation Of Qalementioning

confidence: 99%

Quality-Adjusted Life Expectancy (QALE) and Loss of QALE for Patients With Ischemic Stroke and Intracerebral Hemorrhage

Lee

Hwang

Jeng

et al. 2010

Stroke

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Background and Purpose-Few studies have evaluated the long-term health impact of stroke as categorized into different subtypes. The aim of this study is to quantify the loss of quality-adjusted life expectancy related to ischemic stroke and intracerebral hemorrhage. Methods-The hospital-based cohort, which consisted of 13 194 patients with first-ever stroke onset dates between 1995 and 2007, was classified into lacunar and nonlacunar infarctions and intracerebral hemorrhages. After linking with the National Mortality Registry, survival functions were determined and extrapolated over a 50-year period based on the survival ratio between the patients' survival and age-and sex-matched reference population's as calculated from the vital statistics of Taiwan. The survival functions were then multiplied by the quality of life assessed under the EuroQol 5-dimension (EQ-5D) questionnaire based on a sample of 486 patients with stroke. Results-The quality-adjusted life expectancy for a patient with ischemic stroke was 8.7 quality-adjusted life-years with an average loss of 8.3 quality-adjusted life-years, and there appeared to be no difference between lacunar and nonlacunar infarctions. Patients with intracerebral hemorrhage had a similar quality-adjusted life expectancy as those with ischemic stroke but with a significantly greater loss relative to the reference population (14.1 quality-adjusted life-years) because of younger ages. Conclusion-The lifelong health burden due to stroke was approximately 9.5 quality-adjusted life-years and should be considered in future cost-effectiveness analyses for prevention. (Stroke. 2010;41:739-744.)

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“…The validity of our extrapolation for long-term survival using this statistics package has been validated in previously published studies. [13][14][15] …”

Section: Estimation Of Qalementioning

confidence: 99%

Quality-Adjusted Life Expectancy (QALE) and Loss of QALE for Patients With Ischemic Stroke and Intracerebral Hemorrhage

Lee

Hwang

Jeng

et al. 2010

Stroke

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“…A survival extrapolation method that was created and validated by our study group was applied to estimate the lifetime survival function of this patient cohort [ 11 – 14 ]. The algorithm of how we proceeded is summarized in Fig 1 and as follows:…”

Section: Methodsmentioning

confidence: 99%

“…Since 2006, the members of our research group have already been using this method to measure the LE and EYLL in different clinical scenarios [ 11 – 14 ]. In this report, we present the results of estimating the LE and EYLL of colon cancer patients in Taiwan using our semiparametric method and a nation-wide, population-based cancer registry database from Taiwan.…”

Section: Introductionmentioning

confidence: 99%

Estimation of Life-Year Loss and Lifetime Costs for Different Stages of Colon Adenocarcinoma in Taiwan

2015

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Backgrounds and aimsLife-expectancy of colon cancer patients cannot be accurately answered due to the lack of both large datasets and long-term follow-ups, which impedes accurate estimation of lifetime cost to treat colon cancer patients. In this study, we applied a method to estimate life-expectancy of colon cancer patients in Taiwan and calculate the lifetime costs by different stages and age groups.MethodsA total of 17,526 cases with pathologically verified colon adenocarcinoma between 2002 and 2009 were extracted from Taiwan Cancer Registry database for analysis. All patients were followed-up until the end of 2011. Life-expectancy, expected-years-of-life-lost and lifetime costs were estimated, using a semi-parametric survival extrapolation method and borrowing information from life tables of vital statistics.ResultsPatients with more advanced stages of colon cancer were generally younger and less co-morbid with major chronic diseases than those with stages I and II. The LE of stage I was not significantly different from that of the age- and sex-matched general population, whereas those of stages II, III, and IV colon cancer patients after diagnosis were 16.57±0.07, 13.35±0.07, and 4.05±0.05 years, respectively; the corresponding expected-years-of-life-lost were 1.28±0.07, 5.93±0.07 and 16.42±0.06 years, significantly shorter than the general population after accounting for lead time bias. Besides, the lifetime cost of managing stage II colon cancer patients would be US $8,416±1939, 14,334±1,755, and 21,837±1,698, respectively, indicating a big saving for early diagnosis and treatment after stratification for age and sex.ConclusionsTreating colon cancer at younger age and earlier stage saves more life-years and healthcare costs. Future studies are indicated to apply these quantitative results into the cost-effectiveness evaluation of screening program for colon cancers.

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“…We projected extrapolation of the long‐term survival function beyond the follow up limit using the estimated regression line and the survival curve of the reference population. From this we estimated life expectancy or the lifetime survival function (up to 600 months) after diagnosis [Ho et al, 2006; Fang et al, 2007; Chu et al, 2008a]. The 2000 life‐table of the general population of Mongolia was used to produce the hazard functions of age and gender matched reference subjects [National Statistics Office of Mongolia, 2007].…”

Section: Methodsmentioning

confidence: 99%

Health impact of pneumoconiosis in Mongolia: Estimation of losses in life expectancy and quality adjusted life expectancy

Oyunbileg

Wang

Sumberzul³

et al. 2011

American J Industrial Med

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Estimation of reduced life expectancy from serious occupational injuries in Taiwan

Cited by 15 publications

References 24 publications

Quality-Adjusted Life Expectancy (QALE) and Loss of QALE for Patients With Ischemic Stroke and Intracerebral Hemorrhage

Quality-Adjusted Life Expectancy (QALE) and Loss of QALE for Patients With Ischemic Stroke and Intracerebral Hemorrhage

Estimation of Life-Year Loss and Lifetime Costs for Different Stages of Colon Adenocarcinoma in Taiwan

Health impact of pneumoconiosis in Mongolia: Estimation of losses in life expectancy and quality adjusted life expectancy

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