Estimation of Phytochemical Analysis and Anti-Inflammatory Activity of Fresh Extract of Parmotrema Perlatum and Vitex Negundo

Abstract

Lichens are known for their extraordinary secondary metabolites and thrombolytic activity. Parmotrema perlatum is commonly called Canary moss or Mangalore spices. This lichen is used as tspices in the food in the Indian tradition. The use of P. perlatum in medicine is based on the fact that they contain unique and varied biologically active substances, as natural Antioxidant, Anti-microbial, and Anti-coagulant. Since they are natural anti-biotics, their metabolites exert a wide variety of biological actions including anti-mycotic, antiviral, anti-inflammatory, analgesic, anti-pyretic, anti-proliferative, and cytotoxic effects, they are considered as potential drugs. They contain a variety of secondary metabolites flavonoids, terpenoids, saponins . The lichens can be used as active ingredients for the preparation of drugs for their broad range of activity. The results obtained as a range of phytochemicals like terpenoids, flavonoids, glycosides, carohydrates, proteins were detected in the leaf extracts. Fresh leaves of Parmotrema perlatum and Vitex negundo Aqueous, Chloroform, and Methanol extracts were prepared and used to find out the anti-inflammatory activity of Parmotrema perlatum and Vitex negundo by In Vitro anti-inflammatory method. The study showed significant results.