Estimation of genetic variation in vitiligo associated genes: Population genomics perspective
Neeraj Bharti,
Ruma Banerjee,
Archana Achalare
et al.
Abstract:Background
Vitiligo is an auto-immune progressive depigmentation disorder of the skin due to loss of melanocytes. Genetic risk is one of the important factors for development of vitiligo. Preponderance of vitiligo in certain ethnicities is known which can be analysed by understanding the distribution of allele frequencies across normal populations. Earlier GWAS identified 108 risk alleles for vitiligo in Europeans and East Asians. In this study, 64 of these risk alleles were used for analysing … Show more
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