Estimation of genetic parameters for upper thermal tolerances and growth-related traits in turbot Scophthalmus maximus

Wang, Xinan; Ma, Aijun; Huang, Zhihui; Sun, Zhibin; Cui, Wenxiao; Qu, Junle; Yu, Hong

doi:10.1007/s00343-019-7267-1

Cited by 8 publications

(10 citation statements)

References 31 publications

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“…A selective breeding program for thermotolerance in turbot ( Scophthalmus maximus L.) was carried out at the Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences in 2007 10 . High temperature tolerance strains and sensitive strains were produced by our team, through a series of selection experiments which used survival data and UTT (calculated as cumulative thermal exposure in degree hours) obtained from a thermal challenge 10 , 26 . Following matings, selection for high temperature tolerance strains and sensitive strains were conducted for three successive generations.…”

Section: Methodsmentioning

confidence: 99%

“…associating phenotypes with genotype. According to estimations of genetic parameters for upper thermal tolerance (UTTs) traits, the heritability is low, however, according to the classification levels of Xu et al (2015), UTTs is relative to moderate heritability 9 , 10 . Thus, the construction of high-density genetic linkage maps, and the analysis of quantitative trait loci (QTLs) for marker-assisted selection (MAS) is of significant value, as it accelerates breeding processes, reduces population sizes and breeding costs of bringing progeny to maturity 11 , 12 .…”

Section: Introductionmentioning

confidence: 99%

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Identification of quantitative trait loci associated with upper temperature tolerance in turbot, Scophthalmus maximus

Huang

Wang

et al. 2021

Sci Rep

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Temperature tolerance is an important trait from both an economic and evolutionary perspective in fish. Because of difficulties with measurements, genome-wide selection using quantitative trait loci (QTLs) affecting Upper temperature tolerance may be an alternative for genetic improvement. Turbot Scophthalmus maximus (L.) is a cold-water marine fish with high economic value in Europe and Asia. The genetic bases of upper temperature tolerance (UTTs) traits have been rarely studied. In this study, we constructed a genetic linkage map of turbot using simple sequence repeats (SSRs) and single nucleotide polymorphism (SNP) markers. A total of 190 SSR and 8,123 SNP were assigned to 22 linkage groups (LGs) of a consensus map, which spanned 3,648.29 cM of the turbot genome, with an average interval of 0.44 cM. Moreover, we re-anchored genome sequences, allowing 93.8% physical sequences to be clustered into 22 turbot pseudo-chromosomes. A high synteny was observed between two assemblies from the literature. QTL mapping and validation analysis identified thirteen QLTs which are major effect QTLs, of these, 206 linked SNP loci, and two linked SSR loci were considered to have significant QTL effects. Association analysis for UTTs with 129 QTL markers was performed for different families, results showed that eight SNP loci were significantly correlated with UTT, which markers could be helpful in selecting thermal tolerant breeds of turbot. 1,363 gene sequences were genomically annotated, and 26 QTL markers were annotated. We believe these genes could be valuable candidates affecting high temperatures, providing valuable genomic resources for the study of genetic mechanisms regulating thermal stress. Similarly, they may be used in marker-assisted selection (MAS) programs to improve turbot performance.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Identification of quantitative trait loci associated with upper temperature tolerance in turbot, Scophthalmus maximus

Huang

Wang

et al. 2021

Sci Rep

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“…Employed in quantitative genetic analysis, these parameters can elucidate the proportion of variation of quantitative traits and of co‐variation between two traits (attributed to genetic effects) by estimating variance components (Wang & Ma, 2020; Wang et al, 2019). Reliable estimates of heritability and genetic correlation play a very important role in evaluating breeding values, predicting the response to selection and establishing appropriate breeding programmes (Ma et al, 2018; Sun et al, 2015; Wang & Ma, 2020; Wang et al, 2019). In fact, the accurate estimate of these parameters is directly related to the efficiency of breeding programmes (Wang & Ma, 2020; Wang et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

“…Establishing the genetic variation of economically important traits is a prerequisite for a successful commercial selective breeding programme (Taylor et al, 2009). Thus, estimation of genetic parameters for improved traits is an essential element of fish breeding programmes (Fu et al, 2015;Ma et al, 2018;Sun et al, 2015;Wang et al, 2011Wang et al, , 2019. Within an aquaculture breeding programme, growth traits determine the total harvest yield and are highly desirable as they are associated with high economic benefits.…”

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confidence: 99%

Estimation of genetic parameters for growth traits in cultured Takifugu obscurus

Wang

2021

Aquaculture Research

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The aim of this study was to estimate the genetic parameters of growth performance in Takifugu obscurus. Heritability estimates and genetic correlations were obtained for body weight (BW), body length (BL), total length (TL), chest measurement (CM) and trunk length (TKL). The individuals were measured at the age of 6 and 12 months, and they originated from a nested mating design experimental set up. Estimates were made on data from 50 full‐sib and 25 half‐sib families. The results showed heritability values of 0.280 for BW6, 0.235 for BL6, 0.217 for TL6, 0.246 for CM6, 0.207 for TKL6, 0.240 for BW12, 0.221 for BL12, 0.198 for TL12, 0.230 for CM12 and 0.187 for TKL12. The ranges of genetic correlation estimated within the 6 and the 12 months of age were 0.733–0.971 and 0.155–0.994, respectively, and the range of genetic correlation associated with growth traits between the two ages was 0.097–0.726. The results indicated that genetic improvement for faster growth rate or increased body mass in cultured Takifugu obscures was effective. The selection method for traits with moderate heritability was flexible. Considering that these growth traits did not reach a high level of heritability, family selection should be adopted. Also, as there was a high genetic correlation between BW, BL, TL and CM, these four traits could be improved simultaneously through selective breeding. In addition, CM could be used as a morphological marker of rapid growth for Takifugu obscurus.

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“…Due to its high commercial and nutritional value, turbot is an important cultured species in several European countries and has been introduced into the Southeast Pacific Ocean (Chile) and China for farming. Evaluation of genetic variation and selection for increased growth rates, disease resistance, and temperature tolerance are the main targets of turbot breeding programs (Martínez et al 2016 ; Wang et al 2019 ). Optimal temperature for growth has been reported to range from 13 to 23 °C depending on size (Burel et al 1996 ; Imsland et al 1996 , 2000a ; Árnason et al 2009 ).…”

Section: Introductionmentioning

confidence: 99%

The hemoglobin Gly16β1Asp polymorphism in turbot (Scophthalmus maximus) is differentially distributed across European populations

Andersen

Rubiolo

Rosa³

et al. 2020

Fish Physiol Biochem

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Turbot is an important flatfish widely distributed along the European coasts, whose fishery is centered in the North Sea. The commercial value of the species has boosted a successful aquaculture sector in Europe and China. Body growth is the main target of turbot breeding programs and is also a key trait related to local adaptation to temperature and salinity. Differences in growth rate and optimal growth temperature in turbot have been shown to be associated with a hemoglobin polymorphism reported more than 50 years ago. Here, we identified a Gly16Asp amino acid substitution in the β1 globin subunit by searching for genetic variation in the five functional globin genes within the whole annotated turbot genome. We predicted increased stability of the turbot hemoglobin by the replacement of the conserved Gly with the negative charged Asp residue that is consistent with the higher rate of αβ dimer assembly in the human J-Baltimore Gly16β->Asp mutant than in normal HbA. The turbot Hbβ1-Gly16 variant dominated in the northern populations examined, particularly in the Baltic Sea, while the Asp allele showed elevated frequencies in southern populations and was the prevalent variant in the Adriatic Sea. Body weight did not associate with the Hbβ1 genotypes at farming conditions (i.e., high oxygen levels, feeding ad libitum) after analyzing 90 fish with high growth dispersal from nine turbot families. Nevertheless, all data at hand suggest that the turbot hemoglobin polymorphism has an adaptive significance in the variable wild conditions regarding temperature and oxygen availability.

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Estimation of genetic parameters for upper thermal tolerances and growth-related traits in turbot Scophthalmus maximus

Cited by 8 publications

References 31 publications

Identification of quantitative trait loci associated with upper temperature tolerance in turbot, Scophthalmus maximus

Identification of quantitative trait loci associated with upper temperature tolerance in turbot, Scophthalmus maximus

Estimation of genetic parameters for growth traits in cultured Takifugu obscurus

The hemoglobin Gly16β1Asp polymorphism in turbot (Scophthalmus maximus) is differentially distributed across European populations

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