Abstract. The advanced interferometer network will herald a new era in observational astronomy. There is a very strong science case to go beyond the advanced detector network and build detectors that operate in a frequency range from 1 Hz-10 kHz, with sensitivity a factor ten better in amplitude. Such detectors will be able to probe a range of topics in nuclear physics, astronomy, cosmology and fundamental physics, providing insights into many unsolved problems in these areas.PACS numbers: 95.36.+x, 97.60.Lf, 98.62.Py, 04.80.Nn, 95.55.Ym, 97.60.Bw, 97.60.Jd