The electrocardiogram is generally used clinically in diagnosing the heart diseases. Hence, it must be very accurate. Signals recorded are often contaminated with Power Lime 50 Hz noise and harmonics originating from power supplies, power mains and lights. The presence of noise cormpts the information content of these signals and can degrade the quality of subsequent data analysis. This electrical interference is notoriously difficult to remove without altering the original signal imbedded within the noise. The power line interference reduction in ECG records is a challenging problem which is still open for research. The power line signal, measured directly &om the transmission l i e may have amplitude, phase and frequency variations. This paper deals with designing 50 Hz Twin-T notch filter for elimmating the power line noise from ECG signal. i~b .L+llllr L h 3j % 3 1 3 1 1 ! , &I &Ip\ 4 4 ' &I S! 4 1 YJ j k hi, $ 9 0 .