2012
DOI: 10.1017/s0033291712001717
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Estimating remission from untreated major depression: a systematic review and meta-analysis

Abstract: It is undesirable to expect 100% treatment coverage for depression, given many will remit before access to services is feasible. Data were drawn from consenting wait-list and primary-care samples, which potentially over-represented mild-to-moderate cases of depression. Considering reported rates of spontaneous remission, a short untreated period seems defensible for this subpopulation, where judged appropriate by the clinician. Conclusions may not apply to individuals with more severe depression.

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Cited by 285 publications
(223 citation statements)
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References 62 publications
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“…Aussagen zum Behandlungsbedarf der erfassten depressiven Symptomatik sind nicht direkt ableitbar. So können depressive Symptome als unterschwellige Form einer Depression auftreten und sich häufig auch spontan zurückbilden, so dass kein länger-fristiger Behandlungsbedarf vorliegt [48]. Allerdings wird mit der hier verwendeten Zielvariable auch keine Therapie im umfänglichen Sinne, sondern ein Kontakt zum Hilfesystem abgebildet.…”
Section: Diskussionunclassified
“…Aussagen zum Behandlungsbedarf der erfassten depressiven Symptomatik sind nicht direkt ableitbar. So können depressive Symptome als unterschwellige Form einer Depression auftreten und sich häufig auch spontan zurückbilden, so dass kein länger-fristiger Behandlungsbedarf vorliegt [48]. Allerdings wird mit der hier verwendeten Zielvariable auch keine Therapie im umfänglichen Sinne, sondern ein Kontakt zum Hilfesystem abgebildet.…”
Section: Diskussionunclassified
“…Furthermore, there is evidence that milder cases are more likely to remit without treatment. For cases of depression, the untreated remission rate is 20-30% higher for mild-moderate than for severe disorders (Whiteford et al, 2013). So the marginal gains of further reducing the treatment gap may be small because it will largely involve the milder cases who have less to gain from treatment.…”
Section: Closing the Treatment Gap Mainly Involves Milder Cases Who Hmentioning
confidence: 99%
“…Another factor discussed in this research was depressive symptom improvement, where no significant differences between genders were found, like in a review about improvement in untreated depressive symptoms (Whiteford et al, 2013). In a study performed with depressed individuals receiving citalopram, however, improvement in symptoms measured by the Hamilton scale was greater among women than men.…”
Section: Discussionmentioning
confidence: 76%