Ewes that were untreated, fed lupins or fed lupins and immunized against androstenedione were artificially inseminated. The percentage of ewes pregnant at 36-45 days after insemination (fertility) was 8% higher in ewes that had more than one ovulation than in those that had only one ovulation. Maximum fertility was achieved with 50 x 10(6) spermatozoa and this did not vary with the number of ovulations that ewes had. Among the pregnant, twin-ovulating ewes, embryo survival increased as the number of spermatozoa inseminated increased from 25 x 10(6) to 400 x 10(6). Immunization of ewes against androstenedione increased ovulation rate but reduced fertility, and reduced embryo survival among twin-ovulation ewes.