“…Notably, RSV causes high hospitalization rates in infants [ 8 , 9 , 10 , 11 , 12 ], even healthy children [ 13 , 14 ], without noticeable comorbidities [ 2 , 15 , 16 ], irrespective of their baseline clinical conditions [ 11 , 17 , 18 , 19 ]. Nonetheless, RSV also affects older individuals [ 15 , 20 , 21 , 22 ], where it causes high rates of respiratory illnesses and severe LRTI [ 23 ], particularly in adults aged 75 years or older [ 24 , 25 ], especially among those institutionalized [ 2 , 26 , 27 , 28 ] and/or characterized by pre-existing comorbidities (i.e., chronic obstructive pulmonary disease and congestive heart disorder) [ 22 , 29 , 30 ], with a substantial public health impact [ 31 , 32 , 33 , 34 , 35 , 36 ].…”