Estimación del grosor de la capa lipídica lagrimal mediante colores interferenciales en distintos tipos de ojo seco

García, JS López; Lozano, Isabel; Garchitorena, J Martínez

doi:10.4321/s0365-66912003000500005

Cited by 2 publications

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“…Ñîñòîÿòåëüíîñòü ëèïèäíîãî ñëîÿ ñëåçíîé ïëåíêè (ÑÏ) îöåíèâàëè ïðè ïîìîùè öâåòîâîãî ïîëó-êîëè÷åñòâåííîãî òåñòà íà ëèïèäèíòåðôåðåíöèþ (ïî Norn â ìîäèôèêàöèè J. L pez Garc a è ñîàâò. [18]): êðèòåðèåì íà-ëè÷èÿ ëèïèäîäåôèöèòà ñ÷èòàëè îòñóòñòâèå ôîðìèðîâàíèÿ èíòåðôåðåíöèîííîé êàðòèíû ïðè ñóaeåíèè ãëàçíîé ùåëè íà 50 %, ÷òî ñâèäåòåëüñòâîâàëî î òîëùèíå ëèïèäíîãî ñëîÿ ÑÏ ìåíåå 65 íì. Äëÿ îöåíêè âîäíîãî êîìïîíåíòà ÑÏ ïðîâîäèëè èçìåðåíèå âûñîòû íèaeíåãî ñëåçíîãî ìåíèñêà (ÂÍÑÌ, ìêì) ïðè ïîìîùè îïòè÷åñêîé êîãåðåíòíîé òîìîãðàôèè (OptoVue): êðèòåðèåì âîäîäåôèöèòà áûëà ÂÍÑÌ ìåíåå 250 ìêì [15][16][17].…”

Section: ìàòåðèàë è ìåòîäûunclassified

Ocular surface changes in allergic blepharoconjunctivitis and dry eye syndrome: diagnosis and therapy possibilities

Sakhnov,

Yanchenko,

Malyshev

et al. 2024

Rossijskij oftalʹmologičeskij žurnal

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Purpose: to evaluate the ocular surface changes (OSC) in seasonal and chronic allergic blepharoconjunctivitis (ABC) under dry eye (DE) conditions and to consider therapeutic possibilities.Materials and methods. 60 patients with seasonal ABC and mild DE syndrome (group 1) and 50 patients with chronic ABC and moderate DE syndrome (group 2) were tested for lipid deficiency (LD; negative lipid-interference test), aqua-deficiency (AD; inferior tear meniscus height < 250 ﬁm), and mucose deficiency (Bijsterveld`s xerosis index > 3 scores; XI, scores), Ocular surface disease index (OSDI), tear film break-up time (TBUT, seconds), meibomian gland dysfunction (MGD) according to Korb, taking into account the proportion of MGD (%) and its severity (MGDS, scores), and the “lid-wiper” symptom (LWS, scores) Statistics: M ± s; Mann — Whitney U-test; differences were statistically significant at p < 0.05.Results. LD was diagnosed in 65% of the 1st group patients (OSDI 32.3 ± 4.2, TBUT 6.5 ± 0.6, TMH 363.4 ± 43.96, XI 2.1 ± 0.4, MGDproportion — 41.02 %, LWS 1.1 ± 0.2). LD and MD were detected in 35 % of 1st group patients (OSDI 41.3 ± 5.7, TBUT 5.7 ± 0.5, TMH 332.9 ± 29.9, XI 4.2 ± 0.7, MGD proportion — 61.9 %, LWS 1.24 ± 0.4). The differences in OSDI, TBUT and XI values between DE patients with LD and DE patients with LD and MD were statistically significant. LD and AD were diagnosed in 48 % of 2nd group (OSDI 48.5 ± 6.4, TBUT 5.5 ± 0.6, TMH 192.3 ± 20.8, XI 2.5 ± 0.5, MGDS 1.8 ± 0.4, LWS 1.9 ± 0.3). LD, AD and MD were detected in 52 % of the 2nd group patients (OSDI 57.5 ± 5.8, TBUT 4.6 ± 0.6, TMH 177.7 ± 16.9, XI 5.5 ± 0.6, MGD-S 2.2 ± 0.4, LWS 2.3 ± 0.4). The differences in OSDI, TBUT and XI values between DE patients with LD-AD combination and DE patients with LD-AD-MD were statistically significant.Conclusion. OSC included lipid deficiency (65 %) and lipid-mucose deficiency (35 %) in S-ABC patients; OSC were represented by lipid-aqua-deficiency (48 %) and lipid-aqua-mucose-deficiency (52 %) in C-ABC patients. In our opinion, the diagnostics of these clinical variants of OSP diagnosis, opens up opportunities for differentiated tear replacement therapy. MGD was diagnosed in one half of S-ABC patients and in all C-ABC patients, which we believe determines another possible therapy direction — eyelid therapeutic hygiene aimed at MGD relieving and lipid deficiency compensation.

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Section: ìàòåðèàë è ìåòîäûunclassified

Ocular surface changes in allergic blepharoconjunctivitis and dry eye syndrome: diagnosis and therapy possibilities

Sakhnov,

Yanchenko,

Malyshev

et al. 2024

Rossijskij oftalʹmologičeskij žurnal

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“…En el ojo seco el grosor de la capa lipídica se encuentra disminuido. 16 En circunstancias fisiológicas, la lisozima lagrimal disminuye en el anciano. En circunstancias patológicas la lisozima disminuye en las conjuntivitis y en el ojo seco.…”

Section: Fisiopatología De La Película Lagrimalunclassified

Investigación del consumo de antimicrobianos de uso tópico en España: estudio especial de los colirios y su impacto en situaciones especiales

Sáenz¹

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Estimación del grosor de la capa lipídica lagrimal mediante colores interferenciales en distintos tipos de ojo seco

Cited by 2 publications

References 0 publications

Ocular surface changes in allergic blepharoconjunctivitis and dry eye syndrome: diagnosis and therapy possibilities

Ocular surface changes in allergic blepharoconjunctivitis and dry eye syndrome: diagnosis and therapy possibilities

Investigación del consumo de antimicrobianos de uso tópico en España: estudio especial de los colirios y su impacto en situaciones especiales

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