Esthesioneur oblastoma: Cytologic features with differential diagnostic considerations

Fagan, Marian F.; Rone, R

doi:10.1002/dc.2840010411

Cited by 13 publications

(12 citation statements)

References 10 publications

(1 reference statement)

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“…While some suggestion of nuclear molding within small cell groups was present in our air-dried smears, on alcohol-fixed, H&E-stained slides there was nuclear overlapping in the cell groups rather than nuclear molding. Fagan 8 found nuclear molding infrequently, while Jobst and Collins 1,5 described it as occurring more commonly.…”

Section: Discussionmentioning

confidence: 99%

“…Previous case reports that describe the cytologic findings of ONB strongly support our diagnosis. 1,[3][4][5][6]8 In general, the cytologic features of ONB mimic those of conventional neuroblastoma. [9][10][11][12][13] Overall, authors found single cells and cell groups with a variable number of rosettes or pseudorosettes.…”

Section: Discussionmentioning

confidence: 99%

“…Fagan noted monomorphism with minimal cellular pleomorphism in the aspirates. 8 The nuclei were described as round or oval, with fine to coarsely granular chromatin. Ferris, who directly scraped the nasal tumor, emphasized the fibrillary nature of the cytoplasmic extension in less cohesive clusters of tumor cells.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, these findings were not described in any of the cytologic case reports in the English-language literature. 1,[3][4][5][6][8][9][10] Most ONBs show sufficient histologic features and differentiation to allow a specific diagnosis on the sole basis of light microscopic examination. In Mills' series of 21 cases of ONB, a definitive diagnosis could be made by routine histology in 18 cases, in which a fibrillary, intercytoplasmic background was the most useful diagnostic feature.…”

Section: Discussionmentioning

confidence: 99%

“…Primary ONB diagnosed by fine needle aspiration (FNA) has been reported in only one instance. 6 The cytologic features of ONB have also been described with reference to FNA of a supraclavicular lymph node with pleural fluid analysis 5 and FNA of a recurrent midcervical mass 8 as well as in scrapings from the nasal cavity. 3 The cytomorphologic findings of metastatic ONB involving cervical lymph nodes were described in only two recent papers.…”

Section: Background: Olfactory Neuroblastoma (Onb) Is An Uncommon Tummentioning

confidence: 99%

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Fine Needle Aspiration Cytology of Metastatic Olfactory Neuroblastoma

Chung

Park²,

Jang³

2002

Acta Cytologica

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Background: Olfactory Neuroblastoma (Onb) Is An Uncommon Tummentioning

confidence: 99%

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Fine Needle Aspiration Cytology of Metastatic Olfactory Neuroblastoma

Chung

Park²,

Jang³

2002

Acta Cytologica

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Fine-needle aspiration biopsy cytology of malignant neoplasms of the sinonasal tract

Helsel

Bardales

Mukunyadzi

2003

Cancer

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BACKGROUND Primary and metastatic malignancies that originate in the sinonasal tract are rare and histologically diverse. The role of fine‐needle aspiration biopsy (FNAB) and the cytomorphologic features of these tumors have not been specifically addressed. METHODS The authors reviewed 22 cytology cases (20 FNABs, 1 sputum sample, and 1 pleural fluid sample) from 18 patients with malignancies originating in the sinonasal tract (17 carcinomas, 3 melanomas, and 2 sarcomas) and assessed the cytomorphology, cytohistologic correlation, and ability of cytology to render a specific diagnosis. RESULTS Primary and metastastic sites sampled by FNAB included masses in or around the nose (n = 2), orbit (2), maxillary sinus (2), frontal sinus (1), intraoral area (1), preauricular area (1), soft tissue neck masses, parotid and lymph nodes (10), and cervical spine (1). Exfoliative cytology was positive in two samples of sputum and pleural fluid, representing the initial cancer diagnosis before the sinonasal primary tumor was detected. Seventeen of 22 (77.3%) cases were classified as carcinoma not otherwise specified, carcinoma with specific differentiation, sarcoma, or melanoma. Cytology failed to correctly classify the specific subtype of three carcinomas. The cytologic features that were evaluated included cellularity, cellular arrangement, nuclear features, nuclear‐to‐cytoplasmic ratio, and the background appearance. CONCLUSIONS Sinonasal tract malignancies demonstrate a wide range of cytologic findings but specific features allowing for an accurate and definitive diagnosis are often present in many tumors. Fine‐needle aspiration cytology is an important diagnostic tool in the management of sinonasal malignancies and can be complemented by the use of ancillary studies for the diagnosis of poorly differentiated or nonepithelial tumors. Cancer (Cancer Cytopathol) 2003;99:105–12. © 2003 American Cancer Society.

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Cytopathologic features of olfactory neuroblastoma

Mahooti

Wakely

2006

Cancer

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Polyurethane (PU) composites incorporating Cloisite 15A (15A) were prepared via melt compounding and solvent casting. The melt‐compounded composites had better dispersion and a smaller silicate stack size as a result of the higher shear forces associated with twin‐screw extrusion. The PU microphase separation and hard domain order were greater in the melt‐processed materials. At the concentrations of 15A employed in this study (≤7 wt %), the filler did not have an observable effect on the microphase texture of either the solvent‐ or melt‐processed PU. The tensile properties of the melt‐compounded materials were lower than those of their solvent‐cast counterparts because of thermal degradation. The solvent‐cast composite containing a 3 wt % loading of 15A displayed improved tensile strength and elongation, primarily because of plasticization by the silicate organic treatment. The addition of layered silicates with high aspect ratios increased the hysteresis and permanent set of this PU elastomer. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 97: 300–309, 2005

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Esthesioneur oblastoma: Cytologic features with differential diagnostic considerations

Cited by 13 publications

References 10 publications

Fine Needle Aspiration Cytology of Metastatic Olfactory Neuroblastoma

Fine Needle Aspiration Cytology of Metastatic Olfactory Neuroblastoma

Fine-needle aspiration biopsy cytology of malignant neoplasms of the sinonasal tract

Cytopathologic features of olfactory neuroblastoma

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