Esterase D Polymorphism in Several Population Groups in Israel

Abstract

The genetic polymorphism of red blood cells esterase D (EsD) has been investigated in 9 population groups in Israel: Ashkenazi Jews, non-Ashkenazi Jews from North Africa, Iran, Turkey, Egypt, Balkan, Iraq, Yemen as well as Arabs living in Israel. The distribution of EsD¹and EsD²genes among the 9 communities was not homogenous (χ²= 42.3; d.f. = 8; p < 0.0005). The Ashkenazi and North African Jews had significantly lower frequencies of EsD²(0.100 and 0.102 respectively) than did Yemenite Jews and Arabs (0.212 and 0.206 respectively). The other communities investigated showed intermediate values. A Jewish family from Greece carrying the rare allele EsD³ has been detected.

Genetic Polymorphism of Delta-Aminolevulinate Dehydrase in Several Population Groups in Israel

“…Hemolysates were prepared from blood clots ac cording to the method previously described [5,6], the homogenation being performed with an equal vol ume of 30 m M reduced glutathione solution which prevents ALADH inactivation. Horizontal starch gel electrophoresis (Serva or Connaught starch) and staining procedures were performed as described by Battistuzzi et …”

Phosphoglycolate Phosphatase in Several Population Groups in Israel

“…Hemolysatcs were prepared from blood clots according to the method previously described [3,4], Horizontal starch gel electrophoresis (11.5% electrostarch) was performed according to the method of Barker and Hopkinson [2] at 5 V/cm for 18 h. Their staining procedure using phosphoglycolic acid as substrate was slightly modi fied. The gels were incubated for 90 min with an agar overlay containing the first incubation mix ture.…”