¿Están los grandes repetidores adictos a los comportamientos suicidas?

Blasco-Fontecilla, Hilario; Artieda-Urrutia, Paula; Berenguer-Elias, N.; García-Vega, Juan Manuel; Fernández-Rodríguez, Mónica; Rodriguez-Lomas, Cesar; Gonzalez-Villalobos, Isabel; Iruela-Cuadrado, Luis; León, José de

doi:10.20882/adicciones.38

Cited by 22 publications

(7 citation statements)

References 75 publications

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“…Lin's study also revealed that the number of psychiatric admissions of repeaters was more than that of nonrepeaters, 23 which may indicate that repeaters presented a more severe psychopathology. Repeaters had a trend of shorter follow-up duration in our psychiatric outpatient department compared to nonrepeaters (p=0.419), which might be because a higher proportion of repeaters tend to have more cluster B personality traits, 24 which makes it hard for them to maintain a therapeutic relationship. If the need of suicide repeaters can be discovered and ensured earlier when they encounter psychiatric service, repeated suicide attempts might be preventable.…”

Section: Discussionmentioning

confidence: 93%

<p>Clinical Characteristics of Pesticide Self-Harm as Associated with Suicide Attempt Repetition Status</p>

Huang¹,

Yen²,

Liu³

et al. 2020

NDT

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Purpose: Previous suicide behavior predicts future suicide risk. Studies of suicide repetition are important for suicide prevention. This study examined the clinical characteristics and psychiatric comorbidities of pesticide self-harm as associated with suicide attempt repetition status. Patients and Methods: This retrospective, observational study included patients admitted to a medical center in northern Taiwan between 2000 and 2015 following suicide attempts by pesticide. Diagnoses were made by a consultation-liaison psychiatry team based on the DSM IV-TR criteria. Independent samples t-test was used to analyze the quantitative variables and Pearson's Chi-squared test with a Bonferroni adjustment for categorical variables. Univariate binary logistic regression analysis was conducted to determine the predictors for repeated suicide attempt and multivariate binary logistic regression analysis to identify significant associated factors. Results: Among 151 patients, organophosphate pesticides were the most used (80.8%). The average age was 52.9±17.2 years. Most patients were married males from rural areas, with depressive disorder most often diagnosed (40.4%). Nearly one-third of them were suicide repeaters (n=43, 28.5%); these patients were less likely to be married (53.5%, p=0.001), had previously used psychiatric services (72.1%, p<0.001) and chose complex suicide (46.5%, p=0.014) more often compared to nonrepeaters. No significant differences were found between repeaters and nonrepeaters regarding psychiatric comorbidities. Multivariate logistic regression analysis revealed that marital status (odds ratio: 2.916, 95% confidence interval: 1.234-6.891, p=0.015) and previous psychiatric services usage (odds ratio: 6.897, 95% confidence interval: 3.012-15.625, p<0.001) were significant risk factors associated with suicide repetition. Conclusion: Pesticide suicide repeaters were characterized by less likely to be married and more likely to use psychiatric services before suicide attempts. These features help ensuring that the needs of people who have made a suicide attempt are addressed, and it reduces the likelihood of repetition.

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Section: Discussionmentioning

confidence: 93%

<p>Clinical Characteristics of Pesticide Self-Harm as Associated with Suicide Attempt Repetition Status</p>

Huang¹,

Yen²,

Liu³

et al. 2020

NDT

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“…Most of the participants who engaged in repeated self-harm had low intention to die and the self-harm often resulted from an uncontrollable self-harm urge, as reported in previous research ( 63 ). Previous researchers have even developed instruments to measure the cognitive and emotional aspects of this craving ( 64 ) and repeated self-harm behaviors have been conceptualized as an addiction ( 32 , 34 ). Only one study examined self-harm craving among individuals with frequent self-harm episodes, and reported characteristics similar to addictive behaviors including tolerance, loss of control, and continuation of self-harm behaviors despite significant negative consequences ( 34 ).…”

Section: Discussionmentioning

confidence: 99%

“…Previous researchers have even developed instruments to measure the cognitive and emotional aspects of this craving ( 64 ) and repeated self-harm behaviors have been conceptualized as an addiction ( 32 , 34 ). Only one study examined self-harm craving among individuals with frequent self-harm episodes, and reported characteristics similar to addictive behaviors including tolerance, loss of control, and continuation of self-harm behaviors despite significant negative consequences ( 34 ). The findings of the current study support the notion that individuals with frequent self-harm episodes engage in addictive behaviors relating to self-harm, mostly coexisting with BPD.…”

Section: Discussionmentioning

confidence: 99%

“…Often referred to as major repeaters ( 30 ), these individuals represent a proportion of high suicide risk ( 31 , 32 ). Individuals with frequent self-harm episodes comprise more than 10% of all self-harm presentations ( 29 ), frequently engage with health services ( 33 ) and have difficulties in controlling self-harm behavior, although the broader characteristics of this sub-group are under-researched ( 31 , 32 , 34 ). To our knowledge, only a few studies are available among this group ( 31 , 35 ), and these studies included small samples of individuals with frequent self-harm episodes.…”

Section: Introductionmentioning

confidence: 99%

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Physical and mental illness comorbidity among individuals with frequent self-harm episodes: A mixed-methods study

et al. 2023

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BackgroundResearch has indicated an increased risk of self-harm repetition and suicide among individuals with frequent self-harm episodes. Co-occurring physical and mental illness further increases the risk of self-harm and suicide. However, the association between this co-occurrence and frequent self-harm episodes is not well understood. The objectives of the study were (a) to examine the sociodemographic and clinical profile of individuals with frequent self-harm (regardless of suicidal intent) episodes and, (b) the association between physical and mental illness comorbidity, self-harm repetition, highly lethal self-harm methods, and suicide intent.MethodsThe study included consecutive patients with five or more self-harm presentations to Emergency Departments across three general hospitals in the Republic of Ireland. The study included file reviews (n = 183) and semi-structured interviews (n = 36). Multivariate logistic regression models and independent samples t-tests were used to test the association between the sociodemographic and physical and mental disorders comorbidity on highly lethal self-harm methods and suicidal intent, respectively. Thematic analysis was applied to identify themes related to physical and mental illness comorbidity and frequent self-harm repetition.FindingsThe majority of individuals with frequent self-harm episodes were female (59.6%), single (56.1%), and unemployed (57.4%). The predominant current self-harm method was drug overdose (60%). Almost 90% of the participants had history of a mental or behavioral disorder, and 56.8% had recent physical illness. The most common psychiatric diagnoses were alcohol use disorders (51.1%), borderline personality disorder (44.0%), and major depressive disorder (37.8%). Male gender (OR = 2.89) and alcohol abuse (OR = 2.64) predicted the risk of a highly lethal self-harm method. Suicide intent was significantly higher among those with a diagnosis of major depressive disorder (t = 2.43; p = 0.020). Major qualitative themes were (a) the functional meaning of self-harm (b) self-harm comorbidity (c) family psychiatric history and (d) contacts with mental health services. Participants described experiencing an uncontrollable self-harm urge, and self-harm was referred to as a way to get relief from emotional pain or self-punishment to cope with anger and stressors.ConclusionPhysical and mental illness comorbidity was high among individuals with frequent self-harm episodes. Male gender and alcohol abuse were associated with highly lethal self-harm methods. The mental and physical illness comorbidity of individuals with frequent self-harm episodes should be addressed via a biopsychosocial assessment and subsequent indicated treatment interventions.

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“…Non-suicidal self-injury is the intentional injury of bodily tissues of the self in any way that is not accompanied by suicidal intent (35). It has a high prevalence and potential for future suicidal behavior in adolescent populations worldwide (36,37), and in recent studies it has been found that repetitive non-suicidal self-injury may develop addictive behaviors leading to an increase in frequency and intensity (38,39), with serious implications for adolescent health and life safety. The present study was conducted to verify the significant correlation between non-suicidal self-injury and addiction in a Chinese adolescent population combined with molecular biology experiments to explore clear biomarkers to demonstrate the association between non-suicidal self-injury and addiction.…”

Section: Discussionmentioning

confidence: 99%

Exploring the association of addiction-related genetic factors with non-suicidal self-injury in adolescents

Guo

Liu²,

Wang³

et al. 2023

Front. Psychiatry

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BackgroundNon-suicidal self-injury (NSSI) is self-injurious behavior without suicidal intent commonly seen in the adolescent population and poses a serious threat to the life safety of adolescents. Related researches suggest a possible correlation between addiction and the occurrence of NSSI. This study aimed to explore the correlation between addiction and NSSI from a molecular biological perspective by analyzing the differential expression of addiction-related genes in NSSI patients.Methods(1) The association between addiction and non-suicidal self-injury in a Chinese adolescent population was verified with the help of questionnaires on substance and non-substance addictions and non-suicidal self-injury among 1,329 adolescents in China, (2) Screening for key genes associated with addiction by bioinformatics analysis, and (3) RT-qPCR experiment was performed to validate key genes and Receiver Operating Characteristic curves were plotted for target genes.Results(1) Substance and non-substance addictions were all significantly correlated with non-suicidal self-injury, (2) Four target genes: SERPINA3, SLC14A1, RPS6 and RPS3A were screened by bioinformatics technique, and (3) Relative quantitative analysis by RT-qPCR revealed that the expression levels of SLC14A1 (p < 0.01), RPS6 (p < 0.05) and RPS3A (p < 0.01) were significantly higher in NSSI patients than in healthy controls.Conclusion(1) The significant association between addiction and NSSI exists in the Chinese adolescent population and (2) Addiction-related genes SLC14A1, RPS6, and RPS3A are differentially expressed in adolescents with NSSI. The genes have the potential to become biological markers for the diagnosis of NSSI.

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¿Están los grandes repetidores adictos a los comportamientos suicidas?

Cited by 22 publications

References 75 publications

<p>Clinical Characteristics of Pesticide Self-Harm as Associated with Suicide Attempt Repetition Status</p>

<p>Clinical Characteristics of Pesticide Self-Harm as Associated with Suicide Attempt Repetition Status</p>

Physical and mental illness comorbidity among individuals with frequent self-harm episodes: A mixed-methods study

Exploring the association of addiction-related genetic factors with non-suicidal self-injury in adolescents

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