Estado nutricional, ingesta alimentaria y riesgo de enfermedad cardiovascular en individuos con esquizofrenia en el sur de Brasil: estudio de casos-controles

Nunes, Daniela; Eskinazi, Bianca; Rockett, Fernanda Camboim; Delgado, Vera; Perry, Ingrid Dalira Schweigert

doi:10.1016/j.rpsm.2013.07.001

Cited by 28 publications

(8 citation statements)

References 24 publications

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“…Pela classificação do IMC, 25,34% (n=37) apresentavam sobrepeso e 28,08% (n=41) obesidade (SAMPAIO et al, 2016).Outro estudo, realizado com 25 pacientes esquizofrênicos atendidos no Hospital de Clínicas de Porto Alegre, revelou uma frequência de 40% de sobrepeso e 40% de obesidade, conforme verificado pelo IMC. Entretanto estes pacientes estavam em uso de antipsicóticos(NUNES et al, 2014).…”

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Estado nutricional de portadores de transtornos mentais internados em residências terapêuticas

Manfredi¹,

Alves²,

Marchi³

et al. 2019

RBCEH

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No Brasil, um rápido envelhecimento populacional é observado. Algumas populações possuem características diferentes da população em geral, como taxa de mortalidade, estado nutricional e uso de medicamentos, que é o caso de indivíduos com transtornos mentais. O objetivo deste estudo foi descrever o estado nutricional de indivíduos em tratamento em Residenciais Terapêuticos (RT). Tratase de um estudo transversal com indivíduos com transtornos mentais em tratamento em RT no município de Passo Fundo/RS. Foram entrevistados 68 usuários-moradores e destes, 39,6% (n=17) apresentaram excesso de peso e 30,2% (n=13) obesidade. O uso excessivo de medicamentos surge como um fator determinante para o estado nutricional alterado, visto que todos os indivíduos usam pelo menos um medicamento contínuo e sugerem ter relação com o aumento de peso.

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Estado nutricional de portadores de transtornos mentais internados em residências terapêuticas

Manfredi¹,

Alves²,

Marchi³

et al. 2019

RBCEH

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“…A lower intake of ω-6, phytosterols, vitamin A, and vitamin E (α-tocopherol) has also been reported in relation to BMI and demographically matched comparison subjects (Nunes et al, 2014). In addition, consumption of fruit and vegetable portions is significantly lower that the recommended daily allowance (Heald et al, 2015).…”

Section: Schizophrenia Obesity and Unhealthy Dietary Intakementioning

confidence: 89%

“…Current studies of dietary intake in schizophrenia suggest that most patients have a poor diet largely characterized by increased fast and processed foods (Strassnig et al, 2003), increased sodium and cholesterol intake (Nunes et al, 2014), and higher saturated fat and lower fiber content than non-psychiatric comparison subjects (Brown et al, 1999; Henderson et al, 2006). Although, increased sugar and processed diet consumption is thought to be characteristic of people with schizophrenia originating from Western and European countries (Peet, 2003; Stokes and Peet, 2004), similar findings have also been observed in patients from Eastern countries (Sugawara et al, 2014; Ito et al, 2015).…”

Section: Schizophrenia Obesity and Unhealthy Dietary Intakementioning

confidence: 99%

Modified Mediterranean Diet for Enrichment of Short Chain Fatty Acids: Potential Adjunctive Therapeutic to Target Immune and Metabolic Dysfunction in Schizophrenia?

et al. 2017

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Growing interest in gut and digestive processes and their potential link to brain and peripheral based inflammation or biobehavioral phenotypes has led to an increasing number of basic and translational scientific reports focused on the role of gut microbiota within the context of neuropsychiatric disorders. However, the effect of dietary modification on specific gut metabolites, in association with immune, metabolic, and psychopathological functioning in schizophrenia spectrum disorders has not been well characterized. The short chain fatty acids (SCFA) acetate, butyrate, and propionate, major metabolites derived from fermentation of dietary fibers by gut microbes, interact with multiple immune and metabolic pathways. The specific pathways that SCFA are thought to target, are dysregulated in cardiovascular disease, type II diabetes, and systemic inflammation. Most notably, these disorders are consistently linked to an attenuated lifespan in schizophrenia. Although, unhealthy dietary intake patterns and increased prevalence of immune and metabolic dysfunction has been observed in people with schizophrenia; dietary interventions have not been well utilized to target immune or metabolic illness. Prior schizophrenia patient trials primarily focused on the effects of gluten free diets. Findings from these studies indicate that a diet avoiding gluten benefits a limited subset of patients, individuals with celiac disease or non-celiac gluten sensitivity. Therefore, alternative dietary and nutritional modifications such as high-fiber, Mediterranean style, diets that enrich the production of SCFA, while being associated with a minimal likelihood of adverse events, may improve immune and cardiovascular outcomes linked to premature mortality in schizophrenia. With a growing literature demonstrating that SCFA can cross the blood brain barrier and target key inflammatory and metabolic pathways, this article highlights enriching dietary intake for SCFA as a potential adjunctive therapy for people with schizophrenia.

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“…Essa relação pode ser justificada pelo fato dos pacientes esquizofrênicos apresentarem uma vulnerabilidade associada a polimorfismos genéticos reguladores do comportamento alimentar e da saciedade, e estarem expostos ao uso de múltiplos medicamentos que promovem o ganho de peso corporal (27) .…”

Section: Discussionunclassified

Relação bilateral entre excesso de peso e transtornos mentais

Santos

Nascimento

Cabral

et al. 2018

RBPS

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Este artigo está publicado em acesso aberto (Open Access) sob a licença Creative Commons, que permite uso, distribuição e reprodução em qualquer meio, sem restrições, desde que o trabalho seja corretamente citado. RELAÇÃO BILATERAL ENTRE EXCESSO DE PESO E TRANSTORNOS MENTAIS Bilateral relationship between excess weight and mental disorders Relación bilateral entre el exceso de peso y trastornos mentales

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Estado nutricional, ingesta alimentaria y riesgo de enfermedad cardiovascular en individuos con esquizofrenia en el sur de Brasil: estudio de casos-controles

Cited by 28 publications

References 24 publications

Estado nutricional de portadores de transtornos mentais internados em residências terapêuticas

Estado nutricional de portadores de transtornos mentais internados em residências terapêuticas

Modified Mediterranean Diet for Enrichment of Short Chain Fatty Acids: Potential Adjunctive Therapeutic to Target Immune and Metabolic Dysfunction in Schizophrenia?

Relação bilateral entre excesso de peso e transtornos mentais

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