Abstract:Background: The study aims to use five common pathogenic bacteria in Fracture-related infection (FRI) to establish a simple and fast multiplex qPCR method for initially clinical FRI detection.
Methods: A total of 66 patients with FRI and 24 noninfectious volunteers were enrolled. Results from tissue culture and multiplex qPCR were analyzed and compared. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), Youden Index and area under the ROC curve (AUC) of the two meth… Show more
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