Establishment of humanised xenograft models as in vivo study for lung metastasis of osteosarcoma
Farhana Khamarudin,
Mudiana Muhamad,
Mohamad Johari Ibahim
et al.
Abstract:Humanized xenograft models and cancer cell lines are widely used for preclinical drug evaluation, biological studies, and targeted therapy strategies in cancer research. A humanised mouse model is a laboratory mouse that has been genetically modified to contain specific human genes, cells, or tissues. By introducing human-specific elements into rodents, researchers can create a more accurate representation of human physiological and pathological processes. Lacking an appropriate animal model for osteosarcoma (… Show more
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