Establishment of a Simple, Reproducible, and Long-lasting Hind Limb Animal Model of Lymphedema
Yuichi Morita,
Naoaki Sakata,
Ryo Kawakami
et al.
Abstract:Background:
Lymphedema is an intractable disease for which there is currently no established curative therapy. A reliable and long-lasting lymphedema model is essential for development of better treatments. In this study, we aimed to establish a simple, reproducible and long-lasting mouse model of lymphedema.
Methods:
Our model is characterized by a combination of a circumferential skin incision in the femoral region, complete dissection of regional lym… Show more
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