Establishment of a Novel Overlay Culture Method that Enables Immune Response Assessment Using Gastric Cancer Organoids

Organoids derived from metastatic cancers: Present and future

“…Their size is also limited due to the lack of a vascular network [ 101 ]. Recent studies focusing on developing coculture systems incorporating additional cellular and microbial elements in organoids have shown promising potential [ 73 , 102 ]. Coculturing organoids with other cell types, such as fibroblasts, immune cells and even specific bacteria, could better mimic the complex tumor microenvironment.…”