Establishment and verification of a prognostic model based on coagulation and fibrinolysis-related genes in hepatocellular carcinoma
Meng Fan,
Le Lu,
Hao Shang
et al.
Abstract:Background: Studies have shown that coagulation and fibrinolysis (CFR) are correlated with Hepatocellular carcinoma (HCC) progression and prognosis. We aim to build a model based on CFR-correlated genes for risk assessment and prediction of HCC patient.
Methods: HCC samples were selected from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases respectively. The Molecular Signatures Database (MSigDB) was used to select the CFR genes. RiskScore model were established by single s… Show more
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