Establishment and characterization of a human adenoid cystic carcinoma line of the salivary gland which is serially transplantable and spontaneously metastasises to the lung in nude mice

Nerve Growth Factor and Vascular Endothelial Growth Factor: Retrospective Analysis of 63 Patients with Salivary Adenoid Cystic Carcinoma

“…Salivary adenoid cystic carcinoma (SACC) is a malignant neoplasm that originates in both minor and major salivary glands, characterized by slow growth, diffuse invasion and potential to produce distant metastases, mainly to the lungs and bones (Umeda et al, 2002). Its peculiar biological behaviors always cause great difficulty in treatment and prognosis.…”

Adenoid cystic carcinoma on the dorsum of the tongue

“…ACC is a malignant neoplasm that originates in both the minor and major salivary glands, characterized by slow growth, diffuse invasion, and potential to produce distant metastases, mainly to the lungs and bones. [4] It is an infrequent lesion, as it represents approximately 1-2% of all malignant neoplasms of the head and neck, and up to 10-15% of all malignant salivary gland neoplasms. [5] The most common intra-oral site for minor salivary gland tumors is the hard palate, followed by the base of the tongue[6] where up to 96% of all tumors are malignant, and ACC represents 30% of them.…”

Adenoid cystic carcinoma: A rare late presentation of the mobile tongue

“…1 It is more common in females and characterized by slow indolent growth, affinity for nerve invasion and potential to produce distant metastases, mainly to the lungs and bones. 2 One of the least frequent sites of presentation is the mobile tongue, the incidence of only approximately 3% having being reported. 3…”