Establishing Expectancy Values for Fibrin Monomer in Uncomplicated Pregnancy
Holger Seidel,
Melina Duncklenberg,
Hans-Jörg Hertfelder
et al.
Abstract:Background During pregnancy, a physiological increase of molecular activation markers (MAM) of hemostasis such as prothrombin fragments 1 + 2, thrombin–antithrombin complex, and D-dimers (DD) occurs. Therefore, monitoring MAM levels during pregnancy to evaluate the risk of venous thromboembolism (VTE) may be unreliable; nevertheless, DD analysis in pregnancy is widely performed. In contrast to DD, fibrin monomer (FM) levels have been reported to remain stable during pregnancy.
Objectives The main a… Show more
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