Establishing bilateral modulation of radiation induced redox damage via biocatalytic single atom engineering at Au clusters

Jiao, Menglu; Mu, Xiaoyu; Sun, Si; Yang, H.; Ouyang, Lufei; Zhang, Shaofang; Guo, Jiao; Meng, Jian; Liu, Ya; Ma, Huizhen; Wang, Hao; Pei, Jiahui; Zhao, Ruoli; Li, Tianyu; Long, Wei; Zhang, Xiaodong; Zhang, Ruiping

doi:10.1016/j.cej.2022.136793

Cited by 12 publications

(15 citation statements)

References 73 publications

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“…Second, biocompatibility is important for the development of neuron devices. An electrode can be modified with nanomaterials possessing high catalytic activity, such as nanoclusters 114,[119][120][121][122][123] , atomic level nanozymes 122,[124][125][126][127][128][129] and two-dimensional materials [130][131][132][133] , to reduce the inflammatory response of neural tissue. Third, integrated neuron devices can be developed to achieve multiple functions simultaneously [134][135][136] .…”

Section: Discussionmentioning

confidence: 99%

Neuron devices: emerging prospects in neural interfaces and recognition

et al. 2022

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Neuron interface devices can be used to explore the relationships between neuron firing and synaptic transmission, as well as to diagnose and treat neurological disorders, such as epilepsy and Alzheimer’s disease. It is crucial to exploit neuron devices with high sensitivity, high biocompatibility, multifunctional integration and high-speed data processing. During the past decades, researchers have made significant progress in neural electrodes, artificial sensory neuron devices, and neuromorphic optic neuron devices. The main part of the review is divided into two sections, providing an overview of recently developed neuron interface devices for recording electrophysiological signals, as well as applications in neuromodulation, simulating the human sensory system, and achieving memory and recognition. We mainly discussed the development, characteristics, functional mechanisms, and applications of neuron devices and elucidated several key points for clinical translation. The present review highlights the advances in neuron devices on brain-computer interfaces and neuroscience research.

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Section: Discussionmentioning

confidence: 99%

Neuron devices: emerging prospects in neural interfaces and recognition

et al. 2022

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“…Although surgery, radiotherapy, and chemotherapy, as traditional cancer treatment strategies, have made great contributions to saving the lives of cancer patients, people remain helpless in terms of cancer metastasis and recurrence, which are the main causes of cancer death. 233–238 To overcome the challenges and obtain efficient therapeutic results, tumor immunotherapy is gaining more and more attention as a powerful therapeutic approach by inducing immune memory to eradicate the primary tumor and tumor metastasis. 239–243…”

Section: Current Medical Applicationsmentioning

confidence: 99%

Catalytic nanotechnology of X-ray photodynamics for cancer treatments

Zhang

Guo

et al. 2023

Biomater. Sci.

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“…Nanozymes have received more attention, and hence been developed for applications of biological detection, disease treatment, bacterial inhibition, and other fields, since the discovery of Fe 3 O 4 nanozymes in 2007. − Until date, many inorganic nanomaterials such as precious metals, − metal oxides, , carbon materials, , and their hybrid complexes − have been uncovered to display enzyme-like activities including oxidase, peroxidase, catalase, and superoxide dismutase-mimic properties. Among them, Au nanoparticles are one of the most widely studied nanozymes because of their adjustable catalytic performance and synergistic photothermal capability. , However, Au nanoparticles usually have poor dispersibility and stability, which will lead to compromised catalytic activity .…”

Section: Introductionmentioning

confidence: 99%

Fabrication of Adjustable Au/Carbon Hybrid Nanozymes with Photothermally Enhanced Peroxidase Activity and Ultra-sensitivity for Glutathione Detection

Chen

Qian

et al. 2023

ACS Appl. Mater. Interfaces

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Au nanozymes are extensively researched for their photothermal effect and catalytic performance, but overcoming the inherent defects of poor dispersibility and thermal stability through complementary materials will expand their prospects for biological applications. Herein, several novel CAu nanozymes were fabricated by in situ reduction of chloroauric acid on hollow carbon nanospheres (HCNs). Through regulating the number of reductions, sesame ball-shaped CAu (sCAu) with highly dispersed Au nanoparticles and diversity-shaped CAu (dCAu) were obtained. The number and morphology of loaded Au nanoparticles, absorption spectra, and hydrophilicity of CAu nanozymes were systematically characterized to demonstrate the flexibility of this novel method. The high-efficiency peroxidase-like sCAu0.3 nanozyme with hyperthermia-activated property was then screened for later bio-application. It is worth mentioning that its photothermalpromoted peroxidase-like activity could be achieved under near-infrared laser irradiation. Moreover, sCAu0.3 could specifically achieve glutathione detection in human blood samples. This method will provide a protocol for the regulation of CAu nanozymes to adapt to bio-detection applications.

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Establishing bilateral modulation of radiation induced redox damage via biocatalytic single atom engineering at Au clusters

Cited by 12 publications

References 73 publications

Neuron devices: emerging prospects in neural interfaces and recognition

Neuron devices: emerging prospects in neural interfaces and recognition

Catalytic nanotechnology of X-ray photodynamics for cancer treatments

Fabrication of Adjustable Au/Carbon Hybrid Nanozymes with Photothermally Enhanced Peroxidase Activity and Ultra-sensitivity for Glutathione Detection

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