2017
DOI: 10.5001/omj.2017.45
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Essential Thrombocythemia in a Two-year-old Child, Responsive to Hydroxyurea but Not Aspirin

Abstract: Essential thrombocythemia (ET) is a myeloproliferative neoplasm that occurs mostly in patients above the age of 50 years. Its incidence in children is very rare, with around 100 cases reported in the literature. High-risk patients are defined by previous life threatening major thrombotic or severe hemorrhagic complication or age > 60. Those patients probably benefit from cytoreductive therapy. On the other hand, antiplatelet drugs are recommended for patients with low risk group. Although rare, ET should be co… Show more

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Cited by 7 publications
(18 citation statements)
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“…The results of this present study suggest that AKI is an early complication that commonly happens in the first 90 days and may have a negative effect on prognosis. The overall incidence of AKI during the 3-month follow-up was 31.6%, which is lower than the rates reported in previous research (12, 14). The KDIGO Clinical Practice Guideline for Acute Kidney Injury introduced the RIFLE criteria-Risk, Injury, and Failure; and the two outcome classes: Loss and End-Stage Renal Disease (ESRD) to define AKI and the severity classes (13).…”
Section: Discussioncontrasting
confidence: 73%
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“…The results of this present study suggest that AKI is an early complication that commonly happens in the first 90 days and may have a negative effect on prognosis. The overall incidence of AKI during the 3-month follow-up was 31.6%, which is lower than the rates reported in previous research (12, 14). The KDIGO Clinical Practice Guideline for Acute Kidney Injury introduced the RIFLE criteria-Risk, Injury, and Failure; and the two outcome classes: Loss and End-Stage Renal Disease (ESRD) to define AKI and the severity classes (13).…”
Section: Discussioncontrasting
confidence: 73%
“…In Jordan, descriptive studies and case reports of HSCT in the pediatric population with immunodeficiency disease and malignancies have been conducted. However, more emphasis on HSCT-related morbidity and mortality in adults is warranted (4, 5).…”
Section: Introductionmentioning
confidence: 99%
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“…. Literatürde esansiyel trombositoz insidansı 100000'de 0,6-2,5 olarak bildirilmiştir [5]. Onbir bin altıyüz kırk üç (11643) trombositoz saptanan hastanın tarandığı çalışmamızda esansiyel trombositoz görülmedi.…”
Section: Gereç Ve Yöntemlerunclassified