Essential Oils from Different Myrtaceae Species from Brazilian Atlantic Forest Biome – Chemical Dereplication and Evaluation of Antitrypanosomal Activity

Maiolini, Tatiane C. S.; Rosa, Welton; Miranda, Daniel de Oliveira; Costa-Silva, Thaís A.; Tempone, André G.; Bueno, Paula Carolina Pires; Dias, Danielle Ferreira; Paula, Daniela Aparecida Chagas de; Sartorelli, Patrı́cia; Lago, João Henrique G.; Soares, Marisi G.

doi:10.1002/cbdv.202200198

Cited by 5 publications

(2 citation statements)

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“…Among Myrtaceae genera, Myrcia DC., a heterotypic synonym of Calyptranthes Sw., has been described as occurring in different phytogeographic domains, including Brazilian Atlantic Forest and Brazilian Dry Forest (Santos et al 2023). The chemical composition of the essential oil of some species of the genus Myrcia has also been described (Henriques et al 1997 Maiolini et al 2022). However, to our knowledge, the chemical pro le of the leaf essential oil of Myrcia loranthifolia (DC.)…”

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confidence: 99%

Chemical composition of the essential oil of Myrcia loranthifolia (Myrtaceae) leaves grown in Atlantic Forest and Dry Forest of Brazil

Santos

Silva

Aguiar

et al. 2023

Preprint

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The present study evaluated the chemical composition of the leaf essential oil of Myrcia loranthifolia from Atlantic Forest and Dry Forest of Brazil. The oil showed a mean yield of 0.23–0.33%. From 26 to 32 compounds were identified by GC–MS depending on the geographical origin of the plant. (E)–Caryophyllene (47.80%) and germacrene D (10.07%) predominated in the oil of samples from the Atlantic Forest. In Dry Forest, the main constituent identified in the oil was also (E)–caryophyllene, but it was detected in a lower concentration (15.59%). Cis–calamenene (11.40%), the second major constituent found in the oil of plants from Dry Forest, was not identified in samples from the Atlantic Forest. The qualitative and quantitative differences found may be due to local abiotic factors or inherent to genetic characteristics of the plants. The essential oil of M. loranthifolia constitutes one of the largest sources of (E)–caryophyllene yet unexplored.

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Section: )mentioning

confidence: 99%

Chemical composition of the essential oil of Myrcia loranthifolia (Myrtaceae) leaves grown in Atlantic Forest and Dry Forest of Brazil

Santos

Silva

Aguiar

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…The sampling and analyses of native plants in the current work is authorized by Sistema Nacional de Gestão do Patrimônio Genético e do Conhecimento Tradicional Associado (SisGen), under license permit AD0077F [ 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 …”

mentioning

confidence: 99%

Essential Oils of Aromatic Plant Species from the Atlantic Rainforest Exhibit Extensive Chemical Diversity and Antimicrobial Activity

et al. 2022

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Microbial resistance, caused by the overuse or inadequate application of antibiotics, is a worldwide crisis, increasing the risk of treatment failure and healthcare costs. Plant essential oils (EOs) consist of hydrophobic metabolites with antimicrobial activity. The antimicrobial potential of the chemical diversity of plants from the Atlantic Rainforest remains scarcely characterized. In the current work, we determined the metabolite profile of the EOs from aromatic plants from nine locations and accessed their antimicrobial and biocidal activity by agar diffusion assays, minimum inhibitory concentration, time-kill and cell-component leakage assays. The pharmacokinetic properties of the EO compounds were investigated by in silico tools. More than a hundred metabolites were identified, mainly consisting of sesqui- and mono-terpenes. Individual plants and botanical families exhibited extensive chemical variations in their EO composition. Probabilistic models demonstrated that qualitative and quantitative differences contribute to chemical diversity, depending on the botanical family. The EOs exhibited antimicrobial biocidal activity against pathogenic bacteria, fungi and multiple predicted pharmacological targets. Our results demonstrate the antimicrobial potential of EOs from rainforest plants, indicate novel macromolecular targets, and contribute to highlighting the chemical diversity of native species.

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Chemical composition of the essential oil of Myrcia loranthifolia (Myrtaceae) leaves grown in Atlantic Forest and Dry Forest of Brazil

dos Santos,

de Moura Silva,

de Oliveira Farias de Aguiar

et al. 2023

Braz. J. Bot

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The present study evaluated the chemical composition of the leaf essential oil of Myrcia loranthifolia from Atlantic Forest and Dry Forest of Brazil. The oil showed a mean yield of 0.23-0.33%. From 26 to 32 compounds were identi ed by GC-MS depending on the geographical origin of the plant. (E)-Caryophyllene (47.80%) and germacrene D (10.07%) predominated in the oil of samples from the Atlantic Forest. In Dry Forest, the main constituent identi ed in the oil was also (E)-caryophyllene, but it was detected in a lower concentration (15.59%). Cis-calamenene (11.40%), the second major constituent found in the oil of plants from Dry Forest, was not identi ed in samples from the Atlantic Forest. The qualitative and quantitative differences found may be due to local abiotic factors or inherent to genetic characteristics of the plants. The essential oil of M. loranthifolia constitutes one of the largest sources of (E)-caryophyllene yet unexplored.

show abstract

Essential Oils from Different Myrtaceae Species from Brazilian Atlantic Forest Biome – Chemical Dereplication and Evaluation of Antitrypanosomal Activity

Cited by 5 publications

References 35 publications

Chemical composition of the essential oil of Myrcia loranthifolia (Myrtaceae) leaves grown in Atlantic Forest and Dry Forest of Brazil

Chemical composition of the essential oil of Myrcia loranthifolia (Myrtaceae) leaves grown in Atlantic Forest and Dry Forest of Brazil

Essential Oils of Aromatic Plant Species from the Atlantic Rainforest Exhibit Extensive Chemical Diversity and Antimicrobial Activity

Chemical composition of the essential oil of Myrcia loranthifolia (Myrtaceae) leaves grown in Atlantic Forest and Dry Forest of Brazil

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